Results 51 to 60 of about 576,095 (300)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Applications of knowledge acquisition in experimental software engineering [PDF]
, 1998 Many tasks in experimental software engineering (ESE) involve the acquisition of knowledge. Only for very few of them have systematic knowledge acquisition (KA) practices been established.
Surmann, D. +3 more
core
Replicating software engineering experiments: addressing the tacit knowledge problem [PDF]
, 2022 S.7-16Recently the awareness of the importance of replicating studies has been growing in the empirical software engineering community. The results of any one study cannot simply be extrapolated to all environments because there are many uncontrollable ...
Basili, V. +6 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Empirically-based method for performing qualitative synthesis in software engineering [PDF]
, 2022 Context: In recent years, software researchers begun to benefit from qualitative synthesis to systematically build knowledge about the impact and preconditions of software technologies.
Guzmán Rehbein, Liliana Katherine
core
Utilization of Online Collaborative Tools in Software Engineering: an Empirical Study on Review Meetings [PDF]
, 2021 Software development involves a significant amount of team effort where collaboration and communication of the team members are crucial. The team meetings are core activities in all stages of the software development process.
Hacaloglu,T. +5 more
core +1 more source
Emotion Classification on Software Engineering Q&A Websites
e-Informatica Software Engineering JournalBackground: With the rapid proliferation of question-and-answer websites for software developers like Stack Overflow, there is an increasing need to discern developers’ emotions from their posts to assess the influence of these emotions on their ...
Didi Awovi Ahavi-Tete, Sangeeta Sangeeta
doaj +1 more source
Metabolic Engineering Communications, 2016 Molecular Cloning Designer Simulator (MCDS) is a powerful new all-in-one cloning and genetic engineering design, simulation and management software platform developed for complex synthetic biology and metabolic engineering projects.
Zhenyu Shi, Claudia E. Vickers
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
An approach for quantitative aggregation of evidence from controlled experiments in software engineering [PDF]
, 2013 Empirical studies are necessary to gain reliable insights into the effects of software engineering technologies and to allow controlling risks associated with their usage. Recently, many empirical studies have been run in many software engineering areas (
Ciolkowski, Marcus
core +1 more source