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Emotion Classification on Software Engineering Q&A Websites

e-Informatica Software Engineering Journal
Background: With the rapid proliferation of question-and-answer websites for software developers like Stack Overflow, there is an increasing need to discern developers’ emotions from their posts to assess the influence of these emotions on their ...
Didi Awovi Ahavi-Tete, Sangeeta Sangeeta
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

A Framework for Software Engineering Experimental Replications [PDF]

13th IEEE International Conference on Engineering of Complex Computer Systems (iceccs 2008), 2008
Experimental replications are very important to the advancement of empirical software engineering. Replications are one of the key mechanisms to confirm previous experimental findings. They are also used to transfer experimental knowledge, to train people, and to expand a base of experimental evidence.
Manoel G. Mendonça, José C. Maldonado, Maria C.F. de Oliveira, Jeffrey Carver, Sandra C.P.F. Fabbri, Forrest Shull, Guilherme H. Travassos, Erika Nina Höhn, Victor R. Basili   +8 more
openaire   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Automotive Engineering Drawing Learning: Effective Online Learning Using Autocad Application

Journal of Education Technology, 2021
Learning outcomes are not satisfactory and student learning motivation is low. As a result, students cannot fully master the competency of automotive engineering drawings which are learning outcomes..
Farid Mutohhari, Putu Sudira, Muhammad Nurtanto   +2 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Lexicon-Enhanced LSTM With Attention for General Sentiment Analysis

IEEE Access, 2018
Long short-term memory networks (LSTMs) have gained good performance in sentiment analysis tasks. The general method is to use LSTMs to combine word embeddings for text representation.
Xianghua Fu, Jingying Yang, Jianqiang Li, Min Fang, Huihui Wang   +4 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Computational mechanics in science, applications and teaching [PDF]

Theoretical and Applied Mechanics, 2013
We express our opinion about the role of Computational Mechanics (CM) in science, applications and education. The presented thoughts rely on our experience gained by working over decades (first author in particular) in the field of CM. First, as
Kojić M., Filipović N.
doaj   +1 more source