Results 201 to 210 of about 9,415,293 (298)

Evaluation of Viscosity Reducers for Heavy Oil Reservoirs: Experimental Testing and Numerical Simulation. [PDF]

ACS Omega
Jia Y, Zhang J, Shen N, Xu F, Li J, Zhang P, Zhang C.   +6 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Theoretical Modelling, Experimental Testing and Simulation Analysis of Thermal Properties for Green Building-Insulation Materials. [PDF]

Polymers (Basel)
Balo F.
europepmc   +1 more source

Experimental Test of Utility Maximization

, 2012
The study tests the cardinal utility maximization hypothesis by an experimental procedure in a framework of utility scaling approach following the psychophysical-econometric paradigm, conceived in He (Psychophysical Interpretation for Utility Measures, 2011).
openaire   +3 more sources

Memoria de la Estación Experimental de Aula Dei. 2005. [PDF]

, 2006
CSIC - Estación Experimental de Aula Dei (EEAD)
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Mechanical Characterization and Computational Analysis of TPU 60A: Integrating Experimental Testing and Simulation for Performance Optimization. [PDF]

Materials (Basel)
Lang L, Antunes R, Dutra TA, Aguiar ML, Pereira N, Gaspar PD.   +5 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Experimental Testing on Tuned Liquid Dampers for Implementation in Industrial Chimneys. [PDF]

Sensors (Basel)
Marulli G, Moutinho C.
europepmc   +1 more source

Numerical modeling and experimental testing analysis of Assembled Rubber Metal Isolator. [PDF]

Sci Prog, 2020
Wu J, Liu C, Jiang H, Wang Z.
europepmc   +1 more source