Results 71 to 80 of about 521 (266)
Tradition, experimentalism, innovation. Notes on the edition of Luigi Groto’s theatrical works
Studi Giraldiani, 2020 Questo contributo dà notizia di un progetto, avviato all’Università di Friburgo (Svizzera), incentrato su Luigi Groto e sulla sua produzione teatrale, della quale si prevede di fornire la prima edizione commentata.
Sandra Clerc
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
EXPERIMENTAL HYDROCEPHALUS [PDF]
Journal of Experimental Medicine, 1914 Internal hydrocephalus can be produced experimentally by injecting a foreign substance into the ventricles. In these experiments, aleuronat, a granular, insoluble material, has caused an acute inflammatory reaction, characterized in the first week by an exudate consisting largely of polynuclear leucocytes. Later the picture is one of a chronic process;
openaire +2 more sources
Exploratory experiments and experientia literata: (re) thinking experimentation
Investigações em Ensino de Ciências, 2018 Francis Bacon is sometimes referred to as the first experimental philosopher, and his philosophy is usually tied to the common empirical-inductive idea.
Anabel Cardoso Raicik +2 more
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Experimental Conviviality: Exploring Convivial and Sustainable Practices
Open Cultural Studies, 2020 The paper develops a concept of conviviality as a form of friendly togetherness that includes people, technical infrastructures and nature. Therefore, Marcel Mauss’s concept of the gift, different strands of thinking about conviviality (e.g. Ivan Illich),
Adloff Frank
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source