Results 191 to 200 of about 1,169,893 (336)

The Downside of Experimentation: Evidence from Television Shows

, 2019
Ankur Chavda
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Data-driven methods for exploratory analysis in chemometrics and scientific experimentation

, 2014
Guy Emerton
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

The Trap of Complexity in Experimentation

Yongzhi Huang, Stephen E. Martin, Zhiwei Qin   +2 more
openalex   +1 more source

RaspBed: a low cost experimentation platform based on Raspberry Pi for wireless communication studies [PDF]

, 2019
J. F. Pinheiro, Ezequias Jr, Tarcísio F. Maciel   +2 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Generative artificial intelligence in medical education: moving from potential to practice: when AI surpasses MDs. [PDF]

Can Med Educ J
Morjaria L, Sibbald M.
europepmc   +1 more source

Human Experimentation: Ethics in the Consent Situation [PDF]

, 1967
Fletcher, John
core   +2 more sources

Rapid, low-cost exploration of nucleation rates in l-glutamic acid crystallization in pure media and the presence of polymers through novel parallel experimentation

Khadijeh Firoozirad, Botond Szilágyi
openalex   +1 more source