Results 41 to 50 of about 514,337 (251)

COVID-19 impact on global maritime mobility

open access: yesScientific Reports, 2021
To prevent the outbreak of the Coronavirus disease (COVID-19), many countries around the world went into lockdown and imposed unprecedented containment measures.
Leonardo M. Millefiori   +6 more
doaj   +1 more source

The condition of urban climate experimentation

open access: yesSustainability: Science, Practice, & Policy, 2023
As the trend of urban climate experimentation continues, many accounts now seek to identify how it can be harnessed toward responses of sufficient scale and magnitude for the crises at hand. The imperative is to move beyond experimentation.
Harriet Bulkeley
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Geoengineering as Collective Experimentation [PDF]

open access: yes, 2015
Geoengineering is defined as the 'deliberate and large-scale intervention in the Earth's climatic system with the aim of reducing global warming'. The technological proposals for doing this are highly speculative. Research is at an early stage, but there
Jack Stilgoe, Stilgoe, Jack
core   +2 more sources

Exploratory experimentation and taxonomy of experimentation [PDF]

open access: yesFilozofija i Društvo, 2013
Transformation of the philosophy of science during the last three decades is largely based on the philosophers’ insights in the experimental side of science. Central issues in this new field, such as classification of basic elements and types of
Stojanović Milutin
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Towards Algorithms for Autonomous Experimentation

open access: yes, 2009
1 Introduction Modelling biological systems, is impaired by the cost of experimentally obtaining the data required to build the models. The resources available are typically very limited compared to large experimental parameter spaces, so have to be used
Lovell, C. J., Zauner, K.-P.
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

The Nature and Context of Exploratory Experimentation: An Introduction to Three Case Studies of Exploratory Research [PDF]

open access: yes, 2007
: My aim in this article is to introduce readers to the topic of exploratory experimentation and briefly explain how the three articles that follow, by Richard Burian, Kevin Elliott, and Maureen O’Malley advance our understanding of the nature and ...
Waters, C. Kenneth
core  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Home - About - Disclaimer - Privacy