Results 61 to 70 of about 514,337 (251)

Thermo-Physical and Geotechnical Comparison of Fired Clay Bricks Produced from Oujda and Zayo Soils, Morocco [PDF]

open access: yesE3S Web of Conferences
The use of locally available materials as alternative construction resources represents an effective strategy for reducing building costs and improving the sustainability of construction practices. The present study aims to conduct a comparative analysis
Bensaid Mouaouiya   +6 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Animal Experimentation Ethics Committee B

open access: yes, 2016
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
University of Melbourne. Animal Experimentation Ethics Committee
core  

Generative agents in the streets: Exploring the use of Large Language Models (LLMs) in collecting urban perceptions

open access: yesComputers in Human Behavior: Artificial Humans
Evaluating the surroundings to gain understanding, frame perspectives, and anticipate behavioral reactions is an inherent human trait. However, these continuous encounters are diverse and complex, posing challenges to their study and experimentation ...
Deepank Verma   +2 more
doaj   +1 more source

Artificial Intelligence and Machine Learning in Foot and Ankle Surgery: Current Concepts and Future Directions [PDF]

open access: yesJournal of Foot and Ankle Surgery (Asia Pacific)
Artificial intelligence (AI) technologies have permeated various medical fields, including orthopedics, where they offer advanced methods for diagnosis, treatment, and surgical intervention.
Amit Kumar   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Animal Experimentation Ethics Committee A

open access: yes, 2016
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
University of Melbourne. Animal Experimentation Ethics Committee
core  

Autonomous Experimentation: Active Learning for Enzyme Response Characterisation

open access: yes, 2011
Characterising response behaviours of biological systems is impaired by limited resources that restrict the exploration of high dimensional parameter spaces.
Zauner, Klaus-Peter   +3 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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