Results 51 to 60 of about 514,337 (251)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Experimentation to Reduce Friction from Novel Abrasive Tape Polishing Method [PDF]
, 2010 The aim is to develop and improve a finishing process that allows reduced CO2 emissions, through reduced use of carbon-based fuels, achieving improvement in fuel consumption.
Chen, Xun, Blunt, Liam, Wilkinson, Adam
core +3 more sources
Heterogeneous integrated dataset for Maritime Intelligence, surveillance, and reconnaissance
Data in Brief, 2019 Facing an ever-increasing amount of traffic at sea, many research centres, international organisations, and industrials have favoured and developed sensors together with detection techniques for the monitoring, analysis, and visualisation of sea ...
Cyril Ray +4 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
BioMedical Engineering OnLineThe degeneration of the intervertebral discs in the lumbar spine is the common cause of neurological and physical dysfunctions and chronic disability of patients, which can be stratified into single—(e.g., disc herniation, prolapse, or bulge) and ...
Ichiro Nakamoto +6 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Studies on thermo-oxidative degradation of synthetic rubbers 1-4 and 1-2 polybutadienes
Vietnam Journal of Science, Technology and Engineering, 2017 The production of natural latex is limited, and the related demand for terrestrial transportation has increased. The synthesis of rubber has become necessary and the resulting synthetics’ properties must be known.
Quoc Hung Nguyen +3 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Innovations in Simulation: Experiences with Cloud-based Simulation Experimentation [PDF]
, 2020 The amount of simulation experimentation that can be performed in a project can be restricted by time, especially if a model takes a long time to simulate and many replications are required.
Kiss, T. +10 more
core +1 more source