Results 71 to 80 of about 11,190,422 (282)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Experiments in vortex avalanches

open access: yes, 2004
Avalanche dynamics is found in many phenomena spanning from earthquakes to the evolution of species. It can be also found in vortex matter when a type II superconductor is externally driven, for example, by increasing the magnetic field.
Abrikosov, A. A.   +86 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Effects of wind shear and thrust coefficient on the induction zone of a porous disk: A wind tunnel study

open access: yesWind Energy
Neglecting the velocity reduction in the induction zone of wind turbines can lead to overestimates of power production predictions, and, thus, of the annual energy production for a wind farm.
Wasi Uddin Ahmed, Giacomo Valerio Iungo
doaj   +1 more source

Développement numérique des espaces ruraux

open access: yesNetcom, 2011
There are many concerns caused by the French policy of digital development of country areas, expressed especially by local authorities. Our study tends to understand these reservations and to show how they question geography as well as on-going ...
Jean-Pierre Jambes
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

The joint orchestration of edge applications and UPF CNFs over edge-cloud continuum infrastructure in 6G [PDF]

open access: yesInternational Journal of Electronics and Telecommunications
The paper focuses on future 6G mobile systems deployed over the edge-cloud continuum infrastructure. The challenge is designing an effective orchestration method that allocates instances of edge applications and user plane functions, addressing the ...
Witold Jóźwiak   +2 more
doaj   +1 more source

Experiment.

open access: yes, 2021
Christina West widmet sich in diesem Beitrag der Rolle von Experimenten bei der Wissensproduktion, insbesondere in transdisziplinären Forschungs- und Lehrkontexten. Nach einer allgemeinen Begriffsbestimmung fokussiert sie auf transdisziplinäre Experimente in engerem Sinne, die insbesondere in den transformativen Wissenschaften und in der ...
openaire   +1 more source

Conducting experiments with Experiment Manager [PDF]

open access: yesProceedings of the 28th conference on Winter simulation - WSC '96, 1996
This tutorial demonstrates how to conduct experiments and perform analysis with Experiment Manager, CACI's tool for design and analysis of simulation experiments. Experiment Manager works in conjunction with SIMPROCESS and provides a quick and object oriented approach to designing simulation experiments. The tutorial will describe how to conduct a full
openaire   +1 more source

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