Results 61 to 70 of about 3,549,374 (192)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Ferromagnetic quantum critical point protected by nonsymmorphic symmetry in a Kondo metal

Nature Communications
Quantum critical points (QCPs), zero-temperature phase transitions, are windows to fundamental quantum-mechanical phenomena associated with universal behaviour.
Soohyeon Shin, Aline Ramires, Vladimir Pomjakushin, Igor Plokhikh, Ekaterina Pomjakushina   +4 more
doaj   +1 more source

A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes [PDF]

, 2018
Familial hypercholesterolemia (FH) is mostly caused by low-density lipoprotein receptor (LDLR) mutations and results in an increased risk of early-onset cardiovascular disease due to marked elevation of LDL cholesterol (LDL-C) in blood.
LIU, H, Tian, Xiao-Yu, Au, KW, Ward, C, Tian, XY, Wong, Lai-Yung, Bao, Xichen, Wei, Rui, Ibanez, DP, YANG, J, Luo, Z, Ward, Carl, Tse, Hung-Fat, Bao, X, Liu, Hao, WEI, R, Ho, WI, Ho, Wai-In, Luo, Zhiwei, Huang, Yu, Yang, Jiayin, Huang, Y, Qin, B, Lai, KW, Qin, Baoming, Ibanez, David P., Tse, HF, Lai, Wing-Hon, Esteban, Miguel A., Wong, LY, Au, Ka-Wing, Esteban, MA   +31 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Effects of wind shear and thrust coefficient on the induction zone of a porous disk: A wind tunnel study

Wind Energy
Neglecting the velocity reduction in the induction zone of wind turbines can lead to overestimates of power production predictions, and, thus, of the annual energy production for a wind farm.
Wasi Uddin Ahmed, Giacomo Valerio Iungo
doaj   +1 more source

Spiral-Loop Sequential-Phase-Fed Radial-Sector Patch CP Antenna with Metasurface Superstrate and Parasitic Elements for S-Band CubeSats

Technologies
This work presents a spiral-loop sequential-phase (SLSP)-fed radial-sector patch circularly polarized (CP) antenna for S-band CubeSat platforms. The architecture stacks three RO4003C substrates in an aluminum enclosure: a lower layer with tapered-blade ...
Apiwat Jirawattanaphol, Nathapat Supreeyatitikul, Kentaro Kitamura, Mengu Cho   +3 more
doaj   +1 more source

MSFEB minutes

, 1972
Minutes of the Manned Space Flight Experiments Board: Meeting 72-3 July 14, 1972 at NASA HeadquartersDale D. Myers, Chairman ... [et al.].Biological cosmic radiation effects (BIOCORE) -- Assignment of EREP data-user investigations -- EREP program ...
Myers, Dale D. (Dale Dehaven), 1922-
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

DOE Openness: Human Radiation Experiments

, 2009
This website is the result of a project started in 1994 by the Department of Energy's Office of Human Radiation Experiments. The purpose of the group was to research experiments done to test the effects of radiation on humans and to compile ...
United States. Department of Energy. Office of Human Radiation Experiments.
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