Results 111 to 120 of about 1,576,511 (290)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

INVOLVEMENT OF DIFFERENT STAKEHOLDER GROUPS IN ENSURING CHILDREN’S DENTAL PUBLIC HEALTH: ANALYSIS AND PERSPECTIVES

Клінічна та профілактична медицина
Introduction: Strengthening the dental public health (DPH) of the pediatric population requires prioritizing development with the identification of key stakeholders and their leading functions. The aim.
Lilia V. Kriachkova, Mykhailo Y. Korobko   +1 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Expert Talk given at "Crafting Europe"

https://www.craftingeurope.com/expert-talks/silvia-weidenbach-expert-talks ...
Weidenbach, Silvia
core   +4 more sources

Expert Assessments on Evaluation of Land Use Efficiency in Municipalities of Latvia

Systematic evaluation of land use efficiency allows justifying that the land resources are used for the public benefits. Accordingly, the support for a decision-making at municipal land managemen t level could be provided and the land use in better an d ...
Auziņš, Armands, Geipele, Ineta
core  

Graphical Bayesian models in multivariate expert judgements and conditional external Bayesianity [PDF]

This thesis addresses the multivariate version of the group decision problem (French, 1985), where the opinions about the possible values of n random variables in a problem, expressed as subjective conditional probability density functions of the k ...
Faria, Alvaro Eduardo
core  

Expert system methodologies and applications—a decade review from 1995 to 2004

, 2009
This paper surveys expert systems (ES) development using a literature review and classification of articles from 1995 to 2004 with a keyword index and article abstract in order to explore how ES methodologies and applications have developed during this ...
廖述賢; Liao, Shu-hsien
core   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

EXPERT SYSTEMS [PDF]

In recent decades IT and computer systems have evolved rapidly in economic informatics field. The goal is to create user friendly information systems that respond promptly and accurately to requests.
Mihai Catalin Andrei, Georgiana Marin
core  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source