Results 131 to 140 of about 1,576,511 (290)

Models, systems, networks in economics, engineering, nature and society

open access: yesМодели, системы, сети в экономике, технике, природе и обществе
Background. The article provides an algorithm for determining the optimal management decision when carrying out a project to manufacture a sample of a militaryindustrial complex product at an enterprise of the military-industrial complex.
N.D. Pechalin
doaj   +1 more source

Viewing Expert Judgment in Individual Assessments through the Lens Model: Testing the Limits of Expert Information Processing [PDF]

open access: yes, 2018
University of Minnesota Ph.D. dissertation.May 2018. Major: Psychology. Advisor: Nathan Kuncel. 1 computer file (PDF); vii, 114 pages.The predictive validity of any assessment system is only as good as its implementation.
Yu, Martin
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Expert assessments of the cost and expected future performance of proton exchange membrane fuel cells for vehicles. [PDF]

open access: yesProc Natl Acad Sci U S A, 2019
Whiston MM   +5 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Development of an aircraft design expert system [PDF]

open access: yes, 1988
The aircraft design process is characterised by the application of a wide range of knowledge across many disciplines based upon a certain degree of judgement and experience of the designer. A two pass approach has been taken towards the development of
Alsina, J.
core  

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