Results 91 to 100 of about 2,735,740 (399)
Discussing uncertainty and risk in primary care: recommendations of a multi-disciplinary panel regarding communication around prostate cancer screening. [PDF]
, 2013 BackgroundShared decision making improves value-concordant decision-making around prostate cancer screening (PrCS). Yet, PrCS discussions remain complex, challenging and often emotional for physicians and average-risk men.ObjectiveIn July 2011, the ...Cole, Galen, Plescia, Marcus, Richardson, Lisa C, Srinivasan, Malathi, Tardif, Richard, Wilkes, Michael +5 morecore +1 more sourceEuropean expert consensus on rotational atherectomy
EuroIntervention, 2015 The interest in rotational atherectomy (RA) has increased over the past decade as a consequence of more complex and calcified coronary stenoses being attempted with percutaneous coronary interventions. Yet adoption of RA is hampered by several factors: amongst others, by the lack of a standardised protocol. This European expert consensus document stems Barbato, Emanuele, Carrié, Didier, Dardas, Petros, Fajadet, Jean, Gaul, Georg, Haude, Michael, Khashaba, Ahmed, Koch, Karel, Meyer-Gessner, Markus, Palazuelos, Jorge, Reczuch, Krzysztof, Ribichini, Flavio L, Sharma, Samin, Sipötz, Johann, Sjögren, Iwar, Suetsch, Gabor, Szabó, György, Valdés-Chávarri, Mariano, Vaquerizo, Beatriz, Wijns, William, Windecker, Stephan, de Belder, Adam, Valgimigli, Marco, Byrne, Robert A, Colombo, Antonio, Di Mario, Carlo, Latib, Azeem, Hamm, Christian +27 moreopenaire +5 more sourcesPatient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert +16 morewiley +1 more sourceLasers in melasma: A review with consensus recommendations by Indian pigmentary expert group
Indian Journal of Dermatology, 2017 Lasers have come up as the newest therapeutic modality in dermatological conditions including melasma. In this article, as a group of experts from Pigmentary Disorders Society in collaboration with South Asian Pigmentary Disorders Forum (SPF), we have ...Rashmi Sarkar, Sanjeev Aurangabadkar, T Salim, Anupam Das, Swapnil Shah, Imran Majid, Mohan Singh, G Ravichandran, Kiran Godse, Shehnaz Arsiwala, Latika Arya, Narendra Gokhale, Nilendu Sarma, R G Torsekar, Sidharth Sonthalia, V K Somani +15 moredoaj +1 more sourceExpert consensus statement on therapeutic drug monitoring and individualization of linezolid
Frontiers in Public Health, 2022 Linezolid is an oxazolidinone antibacterial drug, and its therapeutic drug monitoring and individualized treatment have been challenged since its approval.B. Lin, Yangmin Hu, P. Xu, Tao Xu, Chunyan Chen, Lei He, Mi Zhou, Z. Chen, Chunhong Zhang, Xuben Yu, L. Fang, Junfeng Zhu, Y. Ji, Qun Lin, He-qiong Cao, You-Jun Dai, Xiaoyan Lu, Changcheng Shi, Li Li, Changjiang Wang, Xumei Li, Qi Fang, Jing Miao, Zhengyi Zhu, Guangyong Lin, Haichao Zhan, Shiwen Lv, Yalan Zhu, Xin-jun Cai, Yinqing Ying, Meng Chen, Qiong Xu, Yiwen Zhang, Yubin Xu, Pea Federico, Saiping Jiang, Haibin Dai +36 moresemanticscholar +1 more sourceGuidelines for the management of the foot health
problems associated with rheumatoid arthritis [PDF]
, 2011 Background. Rheumatoid arthritis (RA) as a chronic systemic disease, commonly affects the feet, impacting
negatively on patients' quality of life. Specialist podiatrists have a prime role to play in the assessment and
management of foot and ankle ...Bowen, C, Dagg, A, Davies, S, Graham, A, Longrigg, K, Lyons, C, Williams, AE +6 morecore +1 more sourceAggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera +11 morewiley +1 more sourceThe Exeter Activity Unlimited statement on physical activity and exercise for cystic fibrosis: methodology and results of an international, multidisciplinary, evidence-driven expert consensus [PDF]
, 2022 Craig A. Williams, Alan R. Barker, Sarah Denford, Samantha van Beurden, Mayara S. Bianchim, Jessica E. Caterini, Narelle S. Cox, Kelly A. Mackintosh, Melitta A. McNarry, S. Rand, Jane E. Schneiderman, Greg D. Wells, Peter Anderson, Daniel Beever, Z Beverley, Ronan Buckley, Brenda Button, Adam J. Causer, Máire Curran, Tiffany Dwyer, Warren Gordon, Mathieu Gruet, Ryan A. Harris, Elpis Hatziagorou, HJ Hulzebos, Asterios Kampouras, Lisa Morrison, M. Câmara, Clare M Reilly, Abbey Sawyer, Zoe L. Saynor, James Shelley, Grace Spencer, G. Stanford, Don S. Urquhart, Rachel Young, Owen W. Tomlinson +36 moreopenalex +1 more sourceTumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini +12 morewiley +1 more sourceChinese expert consensus on conversion therapy for hepatocellular carcinoma (2021 edition).
Hepatobiliary surgery and nutrition, 2021 Recent advances in systemic and locoregional treatments for patients with unresectable or advanced hepatocellular carcinoma (HCC) have resulted in improved response rates. This has provided an opportunity for selected patients with initially unresectable Hui-Chuan Sun, Jian Zhou, Zheng Wang, Xiufeng Liu, Q. Xie, W. Jia, Ming Zhao, X. Bi, Gong Li, X. Bai, Yuan Ji, Li Xu, Xiao-Dong Zhu, Dou-sheng Bai, Yajin Chen, Yongjun Chen, C. Dai, R. Guo, Wenzhi Guo, C. Hao, Tao Huang, Z. Huang, Deyu Li, Gang Li, Tao Li, Xiangcheng Li, Guangming Li, Xiao Liang, Jingfeng Liu, Fu-bao Liu, Shi-yong Lu, Zheng Lu, Weifu Lv, Y. Mao, G. Shao, Yinghong Shi, T. Song, Guang-xi Tan, Yun-Qiang Tang, K. Tao, C. Wan, Guangyi Wang, Lu Wang, Shunxiang Wang, Tianfu Wen, B. Xing, Bangde Xiang, Sheng Yan, Dinghua Yang, G. Yin, Tao Yin, Z. Yin, Zhengping Yu, Bixiang Zhang, Jialin Zhang, Shuijun Zhang, Ti Zhang, Yamin Zhang, Yubao Zhang, A. Zhang, Haitao Zhao, Ledu Zhou, Wunai Zhang, Zhenyu Zhu, S. Qin, Feng Shen, Xiujun Cai, G. Teng, Jianqiang Cai, Minshan Chen, Qiang Li, Lianxin Liu, Weilin Wang, T. Liang, Jiahong Dong, Xiaoping Chen, Xuehao Wang, Shusen Zheng, Jia Fan +78 moresemanticscholar +1 more source