Results 121 to 130 of about 2,159,559 (302)
Realist Evaluation : an overview [PDF]
This report summarises the discussions and presentations of the Expert Seminar ‘Realist Evaluation’ with Gill Westhorp, which took place in Wageningen on March 29, 2011.
Brouwers, J.H.A.M. +5 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Computer technologies and institutional memory [PDF]
NASA programs for manned space flight are in their 27th year. Scientists and engineers who worked continuously on the development of aerospace technology during that period are approaching retirement.
Bell, Christopher, Lachman, Roy
core +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Relaciones Internacionales, 2009 "Complicidad empresarial y responsabilidad legal", Volumen 2. Derecho penal y crímenes internacionales en "Report of the ICJ Expert Legal Panel on Corporate Complicity in International Crimes".
- Comisión Internacional de Juristas
doaj
, 2015 INTERACT - Researching Third Country Nationals? Integration as a Three-way Process - Immigrants, Countries of Emigration and Countries of Immigration as Actors of Integration The INTERACT project interviewed 24 migration and integration experts across 19 countries in order to better understand the effects of current diaspora and integration policies ...
openaire +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Space station Platform Management System (PMS) replanning using resource envelopes [PDF]
One of the responsibilities of the Space Station Platform Management System (PMS) is to maintain constraint-free, short-term plans for platform and free-flyer activities.
Bush, Joy Lee +2 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source