Results 101 to 110 of about 2,172,368 (301)

Ada issues in implementing ART-Ada [PDF]

open access: yes
Due to the Ada mandate of a number of government agencies, interest in deploying expert systems such as Ada has increased. Recently, several Ada-based expert system tools have been developed.
Lee, S. Daniel
core   +1 more source

An end-to-end machine learning system for harmonic analysis of music

open access: yes, 2011
We present a new system for simultaneous estimation of keys, chords, and bass notes from music audio. It makes use of a novel chromagram representation of audio that takes perception of loudness into account.
De Bie, Tijl   +3 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Some Reflections on the Expert Panel Report on Business Innovation in Canada [PDF]

open access: yesInternational Productivity Monitor, 2009
This article reviews the Council of Canadian Academies Expert Panel report on business innovation. It finds the report comprehensive in its gathering and assessment of available research, innovative, in its own right, in its analysis of innovation as an ...
Ian A. Stewart
doaj  

Can Economic Empowerment Reduce Vulnerability of Girls and Young Women to HIV? [PDF]

open access: yes, 2010
In April 2010, the International Center for Research on Women (ICRW), with support from the Nike Foundation, convened an expert meeting of researchers, program implementers, policymakers and donors to explore emerging insights into the linkages between ...
Ann Warner, Kim Ashburn
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Report of the 5th European expert meeting on rotavirus vaccination (EEROVAC)

open access: yesHuman Vaccines & Immunotherapeutics, 2018
The Fifth European Expert Meeting on Rotavirus Vaccination was convened in Utrecht, The Netherlands, in March 2017. The 2-day meeting included invited lectures as well as original oral and poster presentations and brought together experts from 21 ...
Marieke L. A. de Hoog   +5 more
doaj   +1 more source

Renewable energy target scheme report of the expert panel [PDF]

open access: yes
An examination of the operation, costs and benefits of the RET, including the economic, environmental and social impacts, the extent to which the objectives of the scheme are being met and the interaction of the RET with other Commonwealth and state and ...
Brian Fisher   +3 more
core  

Expert evidence and the Law Commission : implementation without legislation? [PDF]

open access: yes, 2013
Argues that, despite a failure to implement the recommendations in the Law Commission's 2011 report entitled "Expert Evidence in Criminal Proceedings", many of its proposals on the exclusion of such evidence might be introduced by the judiciary's ...
Ward, Tony
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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