Results 101 to 110 of about 480,826 (310)

Research quality framework: assessing the quality and impact of research in Australia - the preferred model

open access: yes, 2005
This paper is part of the development of the the federal government\u27s new Research Quality Framework (RQF) and outlines possible approaches to assessing the quality and impact of original research in Australia.
Expert Advisory Group
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Communication Failure in the Process of Accounting Expertise: A Study in the Region of the High Valley of Itajaí– SC

open access: yesRevista Sociedade, Contabilidade e Gestão, 2013
The number of processes that demand accounting expertise is growing. In the expertise process occur several steps of communication among judges, lawyers, related parts and expert accountant.
Vanderlei dos Santos   +3 more
doaj  

Expert meeting report: epidemiology and management of acquired hypothalamic obesity

open access: yesFrontiers in Endocrinology
Acquired hypothalamic obesity (aHO) is a disease characterized by rapid, clinically significant, and persistent weight gain resulting from damage to hypothalamic structures.
Hermann L. Müller   +10 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Hungry for success A whole school approach to school meals in Scotland

open access: yes, 2003
Final report of the Expert Panel on School Meals. Includes bibliographical referencesAvailable from British Library Document Supply Centre- DSC:m03/15278 / BLDSC - British Library Document Supply CentreSIGLEGBUnited ...
Expert Panel on School Meals (Scotland) (United Kingdom)
core  

Eliciting expert judgement for the probability of AUV loss in contrasting operational environments [PDF]

open access: yes, 2007
Each time an autonomous underwater vehicle (AUV) is used in the sea there is a non-zero probability of loss. Quantifying probability of loss is not an exact science; therefore much depends on the fault history of the vehicle, the operational environment ...
Trembanis, A., Griffiths, G.
core  

Some Reflections on the Expert Panel Report on Business Innovation in Canada [PDF]

open access: yesInternational Productivity Monitor, 2009
This article reviews the Council of Canadian Academies Expert Panel report on business innovation. It finds the report comprehensive in its gathering and assessment of available research, innovative, in its own right, in its analysis of innovation as an ...
Ian A. Stewart
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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