Results 91 to 100 of about 2,172,368 (301)

People in public health. Expert hearings: a summary report [PDF]

open access: yes, 2009
People in Public Health is a national study that is looking at how volunteers and lay workers are involved in improving health in their communities.
Branney, P, Meah, A, South, J
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The Role Of Local Authorities In Health Issues: A Policy Document Analysis [PDF]

open access: yes, 2015
Prior to the passing of the Health and Social Care Act 2012 the Communities and Local Government (CLG) Select Committee conducted an investigation into the proposed changes to the Public Health System in England.
Coleman, A.   +3 more
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Gender and participation in mathematics and further mathematics A-levels: a literature review for the Further Mathematics Support Programme [PDF]

open access: yes, 2014
In preparing this report I have considered evidence from over 60 documents that relate to raising girls’ participation in mathematics. These include published research papers and reports compiled by expert bodies that present an evidence base. Although
Smith, Cathy
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Communication Failure in the Process of Accounting Expertise: A Study in the Region of the High Valley of Itajaí– SC

open access: yesRevista Sociedade, Contabilidade e Gestão, 2013
The number of processes that demand accounting expertise is growing. In the expertise process occur several steps of communication among judges, lawyers, related parts and expert accountant.
Vanderlei dos Santos   +3 more
doaj  

Expert meeting report: epidemiology and management of acquired hypothalamic obesity

open access: yesFrontiers in Endocrinology
Acquired hypothalamic obesity (aHO) is a disease characterized by rapid, clinically significant, and persistent weight gain resulting from damage to hypothalamic structures.
Hermann L. Müller   +10 more
doaj   +1 more source

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