Results 111 to 120 of about 480,826 (310)
Report of the 5th European expert meeting on rotavirus vaccination (EEROVAC)
Human Vaccines & Immunotherapeutics, 2018 The Fifth European Expert Meeting on Rotavirus Vaccination was convened in Utrecht, The Netherlands, in March 2017. The 2-day meeting included invited lectures as well as original oral and poster presentations and brought together experts from 21 ...
Marieke L. A. de Hoog +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
An expert system for hollow extrusion die design [PDF]
This report is based upon a project to develop a prototype expert system to design hollow extrusion dies. Input to the system consisted of a cross sectional representation of the required extruded shape.
Thomas, J. R., Cohn, A. G.
core
The impact of the economic crisis on the situation of women and men and on gender equality policies : synthesis report [PDF]
, 2013 Europe is experiencing a financial and economic crisis. This began with the ‘credit crunch’ in the financial services sector and evolved as a sovereign debt crisis.
Camilleri-Cassar, Frances +7 more
core
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
TWRS vadose zone contamination issue expert panel report
, 1997 When members were first canvassed for participation in the Vadose Zone Expert Panel the stated purpose for convening the Panel was to review a controversial draft report, the SX Tank Farm Report.
Shafer, D. S.
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The Rapid Assessment Workshops to elicit expert input to inform the development of the Great Barrier Reef Outlook Report 2024 [PDF]
The Great Barrier Reef Marine Park Authority (the Reef Authority) convened the rapid assessment workshops in Townsville from 7 to 11 August 2023. The workshops obtained independent expert judgements on the condition, trends, and risks to the Great ...
Boxshall, Anthony, Torok, Simon
core
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source