Results 41 to 50 of about 551,024 (240)

Enhancing emergency medical service diversion decision-making through large language models integration

open access: yesIntelligent Medicine
Objective: Emergency medical services (EMSs) management requires maintaining a delicate balance between time, resources, and quality of care. Rapid and effective decision-making is crucial for patient outcomes.
Zhuyi Shen   +7 more
doaj   +1 more source

Introducing KM Strategic Alignment Road Map in Iranian Public Agencies Studied in Tehran Regional Electricity Company [PDF]

open access: yesJournal of Information Technology Management, 2016
Effective and on time satisfaction of organizational requirements, implementation of KM projects and above all aligning KM with business strategies are the main concerns of executives which make the existence of KM strategic alignment roadmap necessary ...
Mona Jamipor   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

"ELECTRONIC EXPERT" EXPERT SYSTEM SUBSYSTEM'S "DE- SIGN" CONSTRUCTION FEATURES

open access: yesВестник Донского государственного технического университета, 2018
One of the expert system for maintenance service of combine harvester subsystem's structure will be carried out.
L.V. BORISOVA
doaj  

Expert systems utilization in knowledge management

open access: yesAgricultural Economics (AGRICECON), 2006
Knowledge and information are the key to successful pursuit of business activity. For the management knowledge, there can be employed among others the expert systems and eLearning.
V. Vostrovský
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

"ELECTRONIC EXPERT" EXPERT SYSTEM SUBSYSTEM'S "DE- SIGN" CONSTRUCTION FEATURES

open access: yesAdvanced Engineering Research, 2009
One of the expert system for maintenance service of combine harvester subsystem's structure will be carried out.
L.V. BORISOVA
doaj  

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