Results 121 to 130 of about 27,795,417 (374)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Clinical impact of novel cardiovascular and immune system dosimetric parameters in stage III NSCLC patients treated with radiotherapy

open access: yesRadiation Oncology
Purpose To evaluate the clinical impact of the dose to structures not routinely constrained in the radiation treatment (RT) of stage III NSCLC, such as the left anterior descending artery (LAD) and the estimated dose to the immune cells (EDIC). Materials/
Francesco Dionisi   +8 more
doaj   +1 more source

Utilizing expert systems for satellite monitoring and control [PDF]

open access: yes
Spacecraft analysts in the spacecraft control center for the Cosmic Background Explorer (COBE) satellite are currently utilizing a fault-isolation expert system developed to assist in the isolation and correction of faults in the communications link ...
Hughes, Peter M.
core   +1 more source

Artificial Intellignce: Art or Science? [PDF]

open access: yes, 1988
Computer programs are new kinds of machines with great potential for improving the quality of life. In particular, expert systems could improve the ability of the small, weak and poor members of society to access the information they need to solve their ...
Bundy, Alan
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

ART-Ada design project, phase 2 [PDF]

open access: yes
Interest in deploying expert systems in Ada has increased. An Ada based expert system tool is described called ART-Ada, which was built to support research into the language and methodological issues of expert systems in Ada.
Allen, Bradley P., Lee, S. Daniel
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

A System Dynamics Approach to Privatization through Stock Market and Economic Growth in Iran [PDF]

open access: yesپژوهشهای اقتصادی, 2012
The relationship between privatization and economic growth is the main focus of this research. A system dynamics approach and theoretical relationships in macro economics to growth patterns is used to study the impact of privatization through stock ...
Nemat Falihi, Shamsi Morovat
doaj  

A Methodology Based on Expert Systems for the Early Detection and Prevention of Hypoxemic Clinical Cases. [PDF]

open access: yesInt J Environ Res Public Health, 2020
Comesaña-Campos A   +3 more
europepmc   +1 more source

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