Results 121 to 130 of about 10,014,817 (250)
Fuzzy expert system for predicting pathological stage of prostate cancer
, 2015 Prostate cancer is the second most common cancer among men, responsible for the loss of half a million lives each year worldwide, according to the World Health Organization.
Hernandes, F +4 more
core +1 more source
Design and Development of a New Methodology Based on Expert Systems Applied to the Prevention of Indoor Radon Gas Exposition Risks. [PDF]
Int J Environ Res Public Health, 2020 Cerqueiro-Pequeño J +3 more
europepmc +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Modeling the Integration of Expert Systems into Railway Electric Transport Safety Control
Objective of this paper is to examine the principles of expert systems and artificial immune systems and to design a scheme of the transport control system. The authors review the features of expert systems and artificial immune systems and evaluate them
Ļevčenkovs, Anatolijs +1 more
core
Radiation OncologyPurpose To evaluate the clinical impact of the dose to structures not routinely constrained in the radiation treatment (RT) of stage III NSCLC, such as the left anterior descending artery (LAD) and the estimated dose to the immune cells (EDIC). Materials/
Francesco Dionisi +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Multicriterial Methods used in Expert Systems for Business Decision Making [PDF]
Many organizations are in front of most competitive economic environments, where, in order to survive, they must reduce costs all the time and adopt the most intelligent business strategies.
Mihaela MUNTEAN, Cornelia MUNTEAN
core
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source