Results 111 to 120 of about 27,795,417 (374)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

A NEW ALGORITHM FOR GENERATION OF DECISION TREES

open access: yesTASK Quarterly, 2004
A new algorithm for development of quasi-optimal decision trees, based on the Bayes theorem, has been created and tested. The algorithm generates a decision tree on the basis of Bayesian belief networks, created prior to the formation of the decision ...
JERZY W. GRZYMAŁA-BUSSE   +3 more
doaj  

Advanced Machine Learning and Deep Learning Approaches for Estimating the Remaining Life of EV Batteries—A Review

open access: yesBatteries
This systematic review presents a critical analysis of advanced machine learning (ML) and deep learning (DL) approaches for predicting the remaining useful life (RUL) of electric vehicle (EV) batteries.
Daniel H. de la Iglesia   +4 more
doaj   +1 more source

ART-Ada: An Ada-based expert system tool [PDF]

open access: yes
The Department of Defense mandate to standardize on Ada as the language for software systems development has resulted in increased interest in making expert systems technology readily available in Ada environments.
Allen, Bradley P., Lee, S. Daniel
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Strategies for adding adaptive learning mechanisms to rule-based diagnostic expert systems [PDF]

open access: yes
Rule-based diagnostic expert systems can be used to perform many of the diagnostic chores necessary in today's complex space systems. These expert systems typically take a set of symptoms as input and produce diagnostic advice as output.
Bond, W. E.   +3 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

A neural network architecture for implementation of expert systems for real time monitoring [PDF]

open access: yes
Since neural networks have the advantages of massive parallelism and simple architecture, they are good tools for implementing real time expert systems.
Ramamoorthy, P. A.
core   +1 more source

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