Results 101 to 110 of about 10,014,817 (250)

Rule-based expert systems and tonal chord classification

open access: yes, 1999
The purpose of the proposed thesis is to:1. Define expert systems and discuss various implementation techniques for the components of expert systems.
Janidlo, Peter S.
core  

Expert Performance in Information systems [PDF]

open access: yes, 2008
Contrary to the common belief that expert performance is a reflection of innate abilities and capacities, this research demonstrates that expert performance in Information Systems is predominantly mediated by acquired complex skills, expertise, knowledge
Dey, Sharmistha, Sedera, Darshana
core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

“I don’t let anybody die on my watch”: perspectives on the intersection of community overdose response and emergency medical services among people who use drugs in Seattle, WA

open access: yesHarm Reduction Journal
Background The increasing implementation of harm reduction strategies such as take-home naloxone has placed people who use drugs (PWUD) in the position of overdose responders during overdose events, but the perspectives of PWUD are underrepresented in ...
Courteney Wettemann   +11 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

A NEW ALGORITHM FOR GENERATION OF DECISION TREES

open access: yesTASK Quarterly, 2004
A new algorithm for development of quasi-optimal decision trees, based on the Bayes theorem, has been created and tested. The algorithm generates a decision tree on the basis of Bayesian belief networks, created prior to the formation of the decision ...
JERZY W. GRZYMAŁA-BUSSE   +3 more
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

DIAGNOSING SKIN MELANOMA: CURRENT VERSUS FUTURE DIRECTIONS

open access: yesTASK Quarterly, 2003
A new database containing 410 cases of nevi pigmentosi, in four categories: benign nevus, blue nevus, suspicious nevus and melanoma malignant, carefully verified by histopathology, is described. The database is entirely different from the base presented
ZDZISŁAW S. HIPPE   +7 more
doaj  

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