Results 71 to 80 of about 381,856 (249)
Journal of Experimental & Clinical Cancer Research, 2017 Background To assess the oncologic outcomes of hypofractionated whole breast irradiation (Hypo-WBI). Methods Eligible patients had undergone breast conservative surgery for early breast cancer (pTis-2) and none/limited nodal involvement.
Paola Pinnarò +9 more
doaj +1 more source
A systematic review of the applications of Expert Systems (ES) and machine learning (ML) in clinical urology. [PDF]
BMC Med Inform Decis Mak, 2021 Salem H, Soria D, Lund JN, Awwad A.
europepmc +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Applying Machine Learning of Erythrocytes Dynamic Antigens Store in Medicine
Frontiers in Molecular Biosciences, 2019 Erythrocytes Dynamic Antigens Store (EDAS) is a new discovery. EDAS consists of self-antigens and foreign (non-self) antigens. In patients with infectious diseases or malignancies, antigens of infection microorganism or malignant tumor exist in EDAS ...
Mahmoud Rafea +4 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
BatteriesThis systematic review presents a critical analysis of advanced machine learning (ML) and deep learning (DL) approaches for predicting the remaining useful life (RUL) of electric vehicle (EV) batteries.
Daniel H. de la Iglesia +4 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
A NEW ALGORITHM FOR GENERATION OF DECISION TREES
TASK Quarterly, 2004 A new algorithm for development of quasi-optimal decision trees, based on the Bayes theorem, has been created and tested. The algorithm generates a decision tree on the basis of Bayesian belief networks, created prior to the formation of the decision ...
JERZY W. GRZYMAŁA-BUSSE +3 more
doaj
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
DIAGNOSING SKIN MELANOMA: CURRENT VERSUS FUTURE DIRECTIONS
TASK Quarterly, 2003 A new database containing 410 cases of nevi pigmentosi, in four categories: benign nevus, blue nevus, suspicious nevus and melanoma malignant, carefully verified by histopathology, is described. The database is entirely different from the base presented
ZDZISŁAW S. HIPPE +7 more
doaj