Results 51 to 60 of about 97,976 (296)
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
General unsupervised explanatory opinion mining from text data [PDF]
Due to the abundance and rapid growth of opinionated data on the Web, research on opinion mining and summarization techniques has received a lot of attention from industry and academia.
Kim, Hyun Duk
core
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
TEAM-PAIR-SOLO TECHNIQUE TO TEACH READING COMPREHENSION OF EXPLANATORY TEXT
Email: endahworohapsari@rocketmail.com Abstract: The purpose of this research was to investigate the level of the effectiveness of team-pair-solo to teach reading comprehension of explanatory text to Year-X students of “SMA Negeri 8 Pontianak” in ...
Bunau, Eusabinus +2 more
core +1 more source
Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
The role of cognates in reading comprehension: a cognitive perspective [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Programa de Pós-Graduação em Letras/Inglês e Literatura Correspondente.Research on cognates has strongly indicated that there is a close relationship ...
Souza, Vilmar Ferreira de
core
Explanatory constructions in the Altai language (in literary and academic texts) [PDF]
We analyze the structural and semantic types of Altai polypredicative explanatory construc-tions (in literary and academic texts). Explanatory relations are expressed by two types of constructions: monofinite (with the infinite predicate in the subordinate clause) and bifinite (with the finite predicate in the main and subordinate clauses and their ...
openaire +1 more source
How phagocytic cells kill bacteria: Lessons from a professional killer
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
This study aims to compare the writing abilities of students in writing Explanatory Texts using the lecture method and the project-based learning method among eighth-grade students at SMP Negeri 1 Penaggalan for the 2023-2024 academic year.
Nurdiana +2 more
doaj +1 more source

