Results 91 to 100 of about 2,588,745 (274)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
On explicit forms for ergodicity coefficients
Linear Algebra and its Applications, 1993 Suppose \(\| \cdot \|\) is any vector norm on row vectors constituting \(\mathbb{R}^ n\), and \(S_ n\) \((n \geq 2)\) the set of all \(n \times n\) stochastic matrices. The definition of an ergodicity coefficient \(\tau\) for \(P=\{p_{ij}\}\), \(P \in S_ n\) with respect to the norm \(\| \cdot \|\) is \(\tau(P)=\sup \{\| {\underset \sim x}^ T P ...
openaire +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Explicit computation of the Chern character forms [PDF]
Geometriae Dedicata, 2015 14 pages, reference added, typos corrected.
openaire +2 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
IET Control Theory & ApplicationsThis paper proposes explicit solutions for the algebraic Riccati matrix equation. For single‐input systems in controllable canonical form, the explicit Hermitian solutions of the non‐homogeneous Riccati equation are obtained using the entries of the ...
Liangyin Zhang +3 more
doaj +1 more source
A Formulation of an Evolution Equation Governing Magnetic Lines
Journal of Optimization, Differential Equations and Their Applications, 2018 It is shown that `a free function' in the evolution equation of Hornig & Schindler for the magnetic induction (Physics of Plasmas, 3 (3), 781 - 791) has a unique representation, obtained in an explicit form.
Vladimir L. Borsch
doaj +1 more source