Results 91 to 100 of about 294,818 (307)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

From information to knowledge management : a critical approach on differences and common ground under the integration Rhetoric [PDF]

, 2005
It is apparent that the criticism about knowledge management as a fad or a new name for information management is mainly expressed from the information science community.
Μπαλατσούκας, Παναγιώτης
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Knowledge Management: the knowledge value chain

, 2010
Video lecture from a series on Knowledge Management delivered by Dr Alan Eardley. Running time approximately 43 minutes.
Alan Eardley, Staffordshire University
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Knowledge management: re-thinking information management and facing the challenge of managing tacit knowledge

Information Research: An International Electronic Journal, 2002
Knowledge management has generated much interest in recent years and has become the latest management buzz in town. Many people start wondering whether knowledge management is here to stay or it is just another consultancy fad.
Suliman Al-Hawamdeh
doaj  

Working Memory Capacity, TL Grammar Attainment and Length of Study as Predictors of Explicit and Implicit (Automatized) Knowledge of English Passive Voice

Psychology of Language and Communication
This study investigated the relationship between phonological short-term memory (PSTM), working memory capacity (WMC), and receptive and productive dimensions of explicit and implicit (automatized) knowledge of English passive voice, also taking into ...
Biedroń Adriana, Pasikowski Sławomir, Pawlak Mirosław   +2 more
doaj   +1 more source

Emergence of the Cognitive-Emotional Knowledge Dyad [PDF]

Revista de Management Comparat International, 2009
The purpose of this paper is to present the emergence of a new knowledge dyad composed of cognitive and emotional knowledge. The old dyad made of explicit and tacit knowledge may become a particular case of the new one.
Constantin BRĂTIANU , Ivona ORZEA
doaj  

A Hybrid Structure Learning Algorithm for Bayesian Network Using Experts’ Knowledge

Entropy, 2018
Bayesian network structure learning from data has been proved to be a NP-hard (Non-deterministic Polynomial-hard) problem. An effective method of improving the accuracy of Bayesian network structure is using experts’ knowledge instead of only using
Hongru Li, Huiping Guo
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source