Results 51 to 60 of about 110,634 (264)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman +7 more
wiley +1 more source
A coupled implicit-explicit time integration method for compressible unsteady flows [PDF]
Journal of Computational Physics, 2019 This paper addresses how two time integration schemes, the Heun's scheme for explicit time integration and the second-order Crank-Nicolson scheme for implicit time integration, can be coupled spatially. This coupling is the prerequisite to perform a coupled Large Eddy Simulation / Reynolds Averaged Navier-Stokes computation in an industrial context ...
Laurent Muscat +3 more
openaire +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich +5 more
wiley +1 more source
Sensitivity analysis of transient metal forming with incompressible linear elements
Computer Assisted Methods in Engineering and Science, 2023 On the basis of a recently developed method which allows the use of linear elements for metal forming simulation within the flow approach, sensitivity analysis is carried out.
Horacio J. Antúnez
doaj
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Accelerated Runge-Kutta Methods
Discrete Dynamics in Nature and Society, 2008 Standard Runge-Kutta methods are explicit, one-step, and generally constant step-size numerical integrators for the solution of initial value problems. Such integration schemes of orders 3, 4, and 5 require 3, 4, and 6 function evaluations per time step ...
Firdaus E. Udwadia, Artin Farahani
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Systematic Investigation of the Explicit, Dynamically Consistent Methods for Fisher’s Equation
ComputationWe systematically investigate the performance of numerical methods to solve Fisher’s equation, which contains a linear diffusion term and a nonlinear logistic term.
Husniddin Khayrullaev +2 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Applied SciencesIn this paper, a new explicit time integration method for transient heat conduction analysis is proposed based on the uniform trigonometric B-spline function. The algorithmic calculation procedure for solving the heat conduction problem is given.
Zixu Li +3 more
doaj +1 more source