Results 71 to 80 of about 110,634 (264)

An iterative dynamic chemical stiffness removal method for reacting flow simulations

Propulsion and Energy
An iterative dynamic chemical stiffness removal method (IDCSR) based on quasi-steady-state approximation (QSSA) is proposed. The IDCSR method is built on a previously developed non-iterative method which has proved to work well for small timestep sizes ...
Chao Xu, Tianfeng Lu
doaj   +1 more source

Efficient and Stable Time Integration of Cahn–Hilliard Equations: Explicit, Implicit, and Explicit Iterative Schemes

Computational Mathematics and Mathematical Physics
The article proposes a new algorithm for numerical integration over time of the Cahn-Hilliard equation, based on the combined application of the Eyre splitting method and the local iteration modified (LIM) scheme for solving a finite-dimensional problem at each time step.
M. A. Botchev, I. A. Fahurdinov, Evgeny B. Savenkov   +2 more
openaire   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

A class of new nonlinear dynamic integral inequalities containing integration on infinite interval on time scales

Advances in Difference Equations, 2019
In this paper, we investigate some new nonlinear dynamic integral inequalities containing integration on infinite interval on time scales, which provide explicit bounds on unknown functions.
Haidong Liu, Cuiyuan Li, Feichao Shen
doaj   +1 more source

An explicit time integration method for Boussinesq approximation

PAMM
AbstractThis paper presents a novel approach to the discretization of the Boussinesq equation using finite elements, coupled with an explicit pressure correction scheme. The entire numerical scheme is formulated exclusively in terms of matrix‐vector products, enabling a highly efficient numerical solution. The key advantage of this approach lies in its
Dandy Rueda Castillo, Utku Kaya, Thomas Richter   +2 more
openaire   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Stable and Efficient Time Integration of a Dynamic Pore Network Model for Two-Phase Flow in Porous Media

Frontiers in Physics, 2018
We study three different time integration methods for a dynamic pore network model for immiscible two-phase flow in porous media. Considered are two explicit methods, the forward Euler and midpoint methods, and a new semi-implicit method developed herein.
Magnus Aa. Gjennestad, Morten Vassvik, Signe Kjelstrup, Alex Hansen   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source