Results 111 to 120 of about 127,128 (302)

Discrete-Time Implementation of Continuous Terminal Algorithm With Implicit-Euler Method

IEEE Access, 2019
This paper proposes an alternative implementation for a continuous terminal algorithm (CTA) proposed by Torres-Gonzalez et al. The original CTA is a continuous version of the twisting algorithm (TA), which mitigates the chattering by integrating the ...
Xiaogang Xiong, Wei Chen, Shanhai Jin, Shyam Kamal   +3 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

CROSI: Capturing Representing and Operationalising Semantic Integration

, 2005
The University of Southampton and Hewlett Packard Laboratories at Bristol are collaborating in a joint project, CROSI, to investigate semantic integration.
Kalfoglou, Yannis, Hu, Bo, Reynolds, Dave, Shadbolt, Nigel   +3 more
core  

Partitioned Nonlinearity Soil–Structure Interaction Analysis for Nuclear Power Plant Structures with Pile Foundations

Buildings
Accurate seismic safety assessment of nuclear power plant (NPP) structures with pile foundations on soft soil sites requires consideration of soil nonlinearity and pile–soil–structure interaction (PSSI).
Lei Gao, Shaolin Chen
doaj   +1 more source

Understanding science teachers’ implementations of integrated STEM curricular units through a phenomenological multiple case study

International Journal of STEM Education, 2018
Background Current reforms in K-12 STEM education call for integration between science, technology, engineering, and mathematics (STEM). Such integration of STEM disciplines at the K-12 level offers students an opportunity to experience learning in real ...
Emily A. Dare, Joshua A. Ellis, Gillian H. Roehrig   +2 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Explicit Symplectic Integrators with Adaptive Time Steps in Curved Spacetimes

The Astrophysical Journal Supplement Series
Abstract Recently, our group developed explicit symplectic methods for curved spacetimes that are not split into several explicitly integrable parts but are via appropriate time transformations. Such time-transformed explicit symplectic integrators should have employed adaptive time steps in principle, but they are often difficult in ...
Xin Wu, Ying Wang, Wei Sun, Fuyao Liu, Dazhu Ma   +4 more
openaire   +3 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Numerical Solution of Anisotropic Diffusion with Localized Source Using Euler Scheme and Finite Element Method

Berkala Sainstek
This study investigates the numerical modeling of two-dimensional anisotropic diffusion processes involving a spatially localized and temporally limited energy or thermal source.
M. Ziaul Arif, Millatuz Zahroh, Sailah Ar Rizka   +2 more
doaj   +1 more source