Results 91 to 100 of about 127,128 (302)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
A varying time-step explicit numerical integration algorithm for solving motion equation
, 2005 If a traditional explicit numerical integration algorithm is used to solve motion equation in the finite element simu- lation of wave motion, the time-step used by numerical integration is the smallest time-step restricted by the stabil- ity criterion in
尹晓涛 +4 more
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Analysis of Artificial Dissipation of Explicit and Implicit Time-Integration Methods
, 2016 Stability is an important aspect of numerical methods for hyperbolic conservation laws and has received much interest. However, continuity in time is often assumed and only semidiscrete stability is studied. Thus, it is interesting to investigate the influence of explicit and implicit time integration methods on the stability of numerical schemes.
Öffner, Philipp +2 more
openaire +3 more sources
, 2004 Variational integrators are a class of discretizations for mechanical systems which are derived by discretizing Hamilton's principle of stationary action.
West, Matthew
core +1 more source
Time integration algorithms for finite element analysis of creep problems
, 1989 Bibliography: leaves 127-132.The fundamental principles involved in the selection and implementation of time integration schemes for finite element analysis of nonlinear creep problems are investigated.
Marais, Nicholas John
core
Pricing Options under Heston’s Stochastic Volatility Model via Accelerated Explicit Finite Differencing Methods [PDF]
We present an acceleration technique, effective for explicit finite difference schemes describing diffusive processes with nearly symmetric operators, called Super-Time-Stepping (STS).
Conall O'Sullivan, Stephen O'Sullivan
core
, 2010 The present study investigated the binding of verbal and spatial features in immediate memory. In a recent study, we demonstrated incidental and asymmetrical letter-location binding effects when participants attended to letter features (but not when they
Maestú, Fernando +15 more
core +1 more source
Explicit Time Integration of Eddy Current Problems Using a Selective Matrix Update Strategy
, 2016 Purpose Discretizing the magnetic vector potential formulation of eddy current problems in space results in an infinitely stiff differential algebraic equation system that is integrated in time using implicit time integration methods.
Dutiné, Jennifer Susanne +5 more
core +1 more source
A second-order accurate in time IMplicit–EXplicit (IMEX) integration scheme for sea ice dynamics
, 2014 Current sea ice models use numerical schemes based on a splitting in time between the momentum and continuity equations. Because the ice strength is explicit when solving the momentum equation, this can create unrealistic ice stress gradients when using ...
Girard, Claude +3 more
core +1 more source