Results 71 to 80 of about 127,128 (302)
Frontiers in Public Health, 2022 BackgroundEducation nowadays should be a combination of explicit and implicit education, which can effectively improve the effectiveness of ideological and political education, promote the development of ideological and political education in ...
Dong Hui
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Data‐Based Estimation of Critical Time Steps for Explicit Time Integration
International Journal for Numerical Methods in EngineeringABSTRACTFinding the critical time step for conditionally stable time integration methods has been a decades‐long problem. The apparently obvious option of directly computing it from a generalized eigenvalue analysis, identifying the largest eigenfrequency of the discrete system, is usually impractical because of its numerical expense and because a ...
Tobias Willmann +2 more
openaire +2 more sources
MathematicsThe efficiency of various numerical methods for solving Huxley’s equation—which includes a diffusion term and a nonlinear reaction term—is investigated. Conventional explicit finite difference algorithms often suffer from severe stability limitations and
Husniddin Khayrullaev, Endre Kovács
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Energies, 2020 Discontinuous Galerkin (DG) method is a popular high-order accurate method for solving unsteady convection-dominated problems. After spatially discretizing the problem with the DG method, a time integration scheme is necessary for evolving the result ...
Liang Li, Songping Wu
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Sensitivity analysis of transient metal forming with incompressible linear elements
Computer Assisted Methods in Engineering and Science, 2023 On the basis of a recently developed method which allows the use of linear elements for metal forming simulation within the flow approach, sensitivity analysis is carried out.
Horacio J. Antúnez
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Numerical implementation of the eXtended Finite Element Method for dynamic crack analysis [PDF]
, 2008 A numerical implementation of the eXtended Finite Element Method (X-FEM) to analyze crack propagation in a structure under dynamic loading is presented in this paper.
Pantalé, Olivier +2 more
core +1 more source
Explicit Variable Step-Size and Time-Reversible Integration
, 1998 A variable step-size, semi-explicit variant of the explicit Störmer-Verlet method has been proposed for the time-reversible integration of Newton's equations of motion by Huang & Leimkuhler.
Leimkuhler, Benedict +2 more
core +1 more source