Results 81 to 90 of about 127,128 (302)

A Godunov‐type finite‐volume solver for nonhydrostatic Euler equations with a time‐splitting approach

open access: yesJournal of Advances in Modeling Earth Systems, 2017
A two‐dimensional conservative nonhydrostatic (NH) model based on the compressible Euler system has been developed in the Cartesian (x, z) domain. The spatial discretization is based on a Godunov‐type finite‐volume (FV) method employing dimensionally ...
Farshid Nazari, Ramachandran D. Nair
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Comparative Study of Different Time Integration Algorithms for Solving Kinematic Problems

open access: yesModelling
This study selects five numerical methods: the explicit Leap-Frog scheme, the implicit Crank–Nicolson scheme, the explicit second-order Runge–Kutta scheme, the implicit Newmark-β scheme, and the implicit Bathe scheme.
Wei Xu, Yi-Fan Li, Yong-Ou Zhang
doaj   +1 more source

Accelerated Runge-Kutta Methods

open access: yesDiscrete Dynamics in Nature and Society, 2008
Standard Runge-Kutta methods are explicit, one-step, and generally constant step-size numerical integrators for the solution of initial value problems. Such integration schemes of orders 3, 4, and 5 require 3, 4, and 6 function evaluations per time step ...
Firdaus E. Udwadia, Artin Farahani
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Explicit Time Integration Method Based on Uniform Trigonometric B-Spline Function for Transient Heat Conduction Analysis

open access: yesApplied Sciences
In this paper, a new explicit time integration method for transient heat conduction analysis is proposed based on the uniform trigonometric B-spline function. The algorithmic calculation procedure for solving the heat conduction problem is given.
Zixu Li   +3 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Comparative Analysis of ALE Method Implementation in Time Integration Schemes for Pile Penetration Modeling

open access: yesMathematical and Computational Applications
This study investigates the full penetration simulation of piles from the ground surface, focusing on frictional contact modeling without mesh distortion.
Ihab Bendida Bourokba   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

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