Results 101 to 110 of about 933,577 (262)

Mechanism and application of gas phase trapping by spontaneous imbibition

Scientific Reports
For fractured gas reservoirs with strong water drive, gas phase trapping affects the gas recovery significantly. The recovery may be less than 50% for some reservoirs while it is only 12% for Beaver River gas field.
Yujin Wan, Chang He, Xizhe Li, Chunyan Jiao, Xuan Xu, Yong Hu, Yaoqiang Lin   +6 more
doaj   +1 more source

Exploration and Development of a Simpler Respiratory Distress Observation Scale (modRDOS-4) as a Dyspnea Screening Tool: A Prospective Bedside Study. [PDF]

Palliat Med Rep, 2021
Wong RX, Shirlynn H, Koh YS, Goh Seow Lin S, Quah D, Zhuang Q.   +5 more
europepmc   +1 more source

Exploration and exploitation strategies. What kind of analytical models ? [PDF]

This paper gives some insights related to the combination of exploration and exploitation behaviors. A recurrent question for firms deals with this blend of exploration and exploitation mechanisms. Firms are engaged in new activities like research and at
Nadia Jacoby
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Influence of quartz types on mechanical parameters in the early silurian Longmaxi shale, Sichuan Basin

Scientific Reports
Quartz is one of the most abundant minerals in shales, occurring predominantly in three forms: biogenic quartz (BQ), detrital quartz (DQ) and clay-transformed quartz (CTQ).
Qin Zhang, Feng Liang, Qun Zhao, Wen Liu, Weiliang Kong, Wanli Gao, Xinyu Zhang, Guangyin Cai, Tianquan Qu, Zhen Qiu   +9 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

A streamline-based production optimization method for waterflooding reservoirs

Scientific Reports
Waterflooding, the predominant secondary recovery method in global sandstone and carbonate reservoirs, faces challenges including premature water breakthroughs, rapid water cut rise, limited well pattern adjustments and restricted stimulation treatments ...
Lixia Zhang, Yong Li, Xinmin Song, Dandan Hu, Yang Yu, Zeqi Zhao, Wenyu Wang, Chenchao Liu, Miaomiao Lv   +8 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source