Results 121 to 130 of about 933,577 (262)

Weighted mapping of productivity potential based on simulated annealing algorithm for well placement optimization

Journal of Petroleum Exploration and Production Technology
In the realm of reservoir development, the optimization of well placement constitutes a cornerstone challenge with significant implications that directly determine the recovery rate and economic benefits of oil and gas production.
Rui Deng, Bo Kang, Liang Zhang, Lian Wang, Bing Xu, Xing Zhao, Ce Duan   +6 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Elemental logging evidence for paleoenvironmental reconstruction of the ordovician strata in the Western Ordos basin, China

Scientific Reports
The Ordovician carbonate succession in the western Ordos Basin, China, represents an important target for unconventional hydrocarbon exploration, particularly shale gas in the Wulalike Formation.
Zhenyu Zhao, Xia Zhao, Wei Song, Yueqiao Zhang, Jianrong Gao, Yuanshi Sun, Zhaobing Chen   +6 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

A 500‐kyr Pluvial Interval Triggered Lacustrine Carbon Burial in Late Cretaceous East Asia

Geophysical Research Letters
The early Late Cretaceous hothouse was featured by intense storms and a prevailing monsoon climate, yet direct evidence for regional extreme precipitation events is rare.
Yuke Liu, Xiaomei Wang, Minghao Wu, Jin Su, Chengshuai Yuan, Xuening Qi, Shuichang Zhang   +6 more
doaj   +1 more source

An exploration of the impact of role modelling on adult nursing students' professional development [PDF]

, 2013
Service users expect to be cared for by a nurse who is both competent and professional, a particularly pertinent point following the Francis and Keogh reports (DH 2013a, DH 2013b).
Felstead, I.
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Genesis of high-quality ultra-thick glutenite reservoirs: coupled control of sedimentation and diagenesis

Journal of Petroleum Exploration and Production Technology
As a distinctive type of oil and gas reservoir, ultra-thick glutenite reservoirs are characterized by strong heterogeneity and complex diagenetic evolution, making the prediction of high-quality intervals particularly challenging.
Yuxin Liang, Xinmin Song, Youjing Wang, Hualing Zhang, Jie Wang   +4 more
doaj   +1 more source