Results 111 to 120 of about 2,643,922 (315)

The Practitioner\u27s Corner: An exploration of municipal active living charter development and advocacy [PDF]

open access: yes, 2013
Background: Numerous municipal active living-­‐related charters have been adopted to promote physical activity in Canada throughout the past decade. Despite this trend, there are few published critical examinations of the process through which charters ...
Benson, Alex J   +4 more
core   +1 more source

Social decision-making driven by artistic explore-exploit tension

open access: yes, 2018
We studied social decision-making in the rule-based improvisational dance $There$ $Might$ $Be$ $Others$, where dancers make in-the-moment compositional choices. Rehearsals provided a natural test-bed with communication restricted to non-verbal cues.
Dey, Biswadip   +5 more
core   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1535-1555, June 2026.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Influence of quartz types on mechanical parameters in the early silurian Longmaxi shale, Sichuan Basin

open access: yesScientific Reports
Quartz is one of the most abundant minerals in shales, occurring predominantly in three forms: biogenic quartz (BQ), detrital quartz (DQ) and clay-transformed quartz (CTQ).
Qin Zhang   +9 more
doaj   +1 more source

Growth through Heterogeneous Innovations [PDF]

open access: yes
We study how exploration versus exploitation innovations impact economic growth through a tractable endogenous growth framework that contains multiple innovation sizes, multi-product firms, and entry/exit.
Ufuk Akcigit, William R. Kerr
core  

From Pythagoras to Johann Sebastian Bach: An Exploration in the Development of Temperament and Tuning [PDF]

open access: yes, 2014
Temperament and tuning are at the core of all music—they are the embodiment of the correlation of music and mathematics in every musical work. In examining the shift from Pythagorean tuning to well temperament, compositional style and philosophy governs ...
Anderson, Molly
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Group-Level Exploration and Exploitation: A Computer Simulation-Based Analysis [PDF]

open access: yes
Organisational research has studied the tension between exploration and exploitation for years. In essence, this body of research agrees on the necessity of a balance between explora-tive and exploitative processes to prevent an organisation from falling
Jennifer Kunz
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

A streamline-based production optimization method for waterflooding reservoirs

open access: yesScientific Reports
Waterflooding, the predominant secondary recovery method in global sandstone and carbonate reservoirs, faces challenges including premature water breakthroughs, rapid water cut rise, limited well pattern adjustments and restricted stimulation treatments ...
Lixia Zhang   +8 more
doaj   +1 more source

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