Results 111 to 120 of about 2,621,041 (313)
Growth through Heterogeneous Innovations [PDF]
We study how exploration versus exploitation innovations impact economic growth through a tractable endogenous growth framework that contains multiple innovation sizes, multi-product firms, and entry/exit.
Ufuk Akcigit, William R. Kerr
core
Exploring Oculus Rift: A Historical Analysis of the ‘Virtual Reality’ Paradigm [PDF]
, 2017 This paper will first provide background information about Virtual Reality in order to better analyze its development throughout history and into the future.
Gammage, Chastin
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
A streamline-based production optimization method for waterflooding reservoirs
Scientific ReportsWaterflooding, the predominant secondary recovery method in global sandstone and carbonate reservoirs, faces challenges including premature water breakthroughs, rapid water cut rise, limited well pattern adjustments and restricted stimulation treatments ...
Lixia Zhang +8 more
doaj +1 more source
Approaches to flame resistant polymeric materials [PDF]
Four research and development areas are considered for further exploration in the quest of more flame-resistant polymeric materials. It is suggested that improvements in phenolphthalein polycarbonate processability may be gained through linear free ...
Liepins, R.
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Extraterrestrial imperative [PDF]
The future benefits of extraterrestrial space to man and his problems, both personal and environmental, are discussed. Particular attention was given to space manufacturing, development of space power plants, mineral exploration, and transportation costs
Ehricke, K. A.
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Significant achievements in the planetary geology program, 1975 - 1976 [PDF]
Developments in planetology research as reported at the 1976 NASA Planetology Program Principal Investigators' meeting are summarized. Topics range from solar system evolution, comparative planetology, and geologic processes to techniques and instrument ...
Head, J. W.
core +1 more source