Results 141 to 150 of about 17,950 (315)

Planetary Protection and the astrobiological exploration of Mars: Proactive steps in moving forward. [PDF]

Adv Space Res, 2019
Fairén AG, Schulze-Makuch D, Whyte L, Parro V, Pavlov A, Gómez-Elvira J, Azua-Bustos A, Fink W, Baker V.   +8 more
europepmc   +1 more source

Mars as a Planet B?

International audienceThe concept of terraforming Mars has been popularized in pop culture and recently by Elon Musk. The objective is to transform Mars into a planet suitable for habitation by living organisms and humans.
Forget, Francois, Lee, Natuschka M.,, Mangold, Nicolas, Tønnessen, Morten, Sivula, Oskari, Tönnessen, Morten, Freissinet, Caroline, Persson, Erik, Barthomeuf, Perrine, Lee, Natuschka   +9 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Dust removal on solar panels of exploration rovers using Chladni patterns

Scientific Reports
The buildup of dust on solar panels has significantly reduced the operational lifespan and mission performance of exploration rovers, and traditional dust removal techniques have proven inadequate for the Martian environment. The present study proposes a
Hyunsung Cho, Jungyu Woo, Junyeong Park, Jinung Lee, Seongpil Cho   +4 more
doaj   +1 more source

The BASALT Research Program: Designing and Developing Mission Elements in Support of Human Scientific Exploration of Mars. [PDF]

Astrobiology, 2019
Lim DSS, Abercromby AFJ, Kobs Nawotniak SE, Lees DS, Miller MJ, Brady AL, Miller MJ, Mirmalek Z, Sehlke A, Payler SJ, Stevens AH, Haberle CW, Beaton KH, Chappell SP, Hughes SS, Cockell CS, Elphic RC, Downs MT, Heldmann JL.   +18 more
europepmc   +1 more source

Extension of Martian orbits using continuous low-thrust propulsion

, 2012
There has recently been significant interest in exploration of the Martian surface and atmosphere with a view to future human exploration. Thus missions must be developed which are responsive to these scientific goals.
Macdonald, Malcolm, Anderson, Pamela, Yen, Chen-wan L.   +2 more
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

A Low-Diversity Microbiota Inhabits Extreme Terrestrial Basaltic Terrains and Their Fumaroles: Implications for the Exploration of Mars. [PDF]

Astrobiology, 2019
Cockell CS, Harrison JP, Stevens AH, Payler SJ, Hughes SS, Kobs Nawotniak SE, Brady AL, Elphic RC, Haberle CW, Sehlke A, Beaton KH, Abercromby AFJ, Schwendner P, Wadsworth J, Landenmark H, Cane R, Dickinson AW, Nicholson N, Perera L, Lim DSS.   +19 more
europepmc   +1 more source