Results 121 to 130 of about 17,950 (315)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
International Journal of Advanced Robotic Systems, 2018 As a class of autonomous deep-space exploration robots, Mars lander is simultaneously affected by wind disturbance and actuator fault, which hinders precise landing on Mars.
Jianwei Xu, Jianzhong Qiao, Lei Guo
doaj +1 more source
Mars Human Exploration Reference Mission
, 1998 This presentation proposes the next steps for human exploration of Mars. The presentation reviews the reasons for human exploration of Mars. Two different trajectories are proposed: (1) for a long stay mission, and (2) for a short term mission, which ...
Drake, Bret
core
A proposal for control system of a wind energy convertion system for special purposes [PDF]
, 2011 Nuclear energy sources have been widely used in the past decades in order to power the spacecrafts, nevertheless their use has attracted controversy because of the risk of harmful material released into the atmosphere if an accident were to occur during ...
Cescon, Marco
core
, 2020 More than 50 years after the Mariner 4 flyby on 15 July 1965, Mars still represents the next frontier of space explorations. Of particular focus nowadays is crewed missions to the red planet.
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Challenges of Mars Exploration
, 2019 The quest for Mars exploration stands as a testament to humanity's enduring interest and ambition to traverse new frontiers. Mars, the fourth planet from the Sun, gives a fascinating yet formidable target for exploration and capacity colonization.
Girdhari Jangid, Mini Sengar
openaire +2 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
MeSat Mission: Exploring Martian Environment with THz Radiometer Payload and Optimal Trajectory
Remote SensingSpace exploration presents vast prospects for scientific, industrial, and economic progress. This paper introduces the MeSat mission as a pioneering approach to Mars exploration.
Vahid Rastinasab +4 more
doaj +1 more source