Results 141 to 150 of about 304,850 (274)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Artificial intelligence and academic writing questionnaire (AI-AWQ): development and validation among medical students' experiences using exploratory factor analysis. [PDF]

BMC Med Educ
Khojasteh L, Karimian Z, Nasiri E, Kafipour R, Farahmandi AY.   +4 more
europepmc   +1 more source

Reassessment of innovative methods to determine the number of factors: A simulation-based comparison of Exploratory Graph Analysis and Next Eigenvalue Sufficiency Test.

, 2022
Nils Brandenburg, Martin Papenberg
openalex   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Identification of Factor Scores by Regression with External Variables in Exploratory Factor Analysis. [PDF]

Psychometrika
Yamashita N.
europepmc   +1 more source

Neurotransmitters and the Behavior of Individual Investors: Exploratory and Confirmatory Factor Analysis [PDF]

Mohammad Nazaripour, Babak Zakizadeh
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

An exploratory factor analysis of nutritional biomarkers associated with major depression in pregnancy [PDF]

, 2011
Lisa M. Bodnar, Katherine L. Wisner, James F. Luther, Robert W. Powers, Roger G. Evans, Marcia J. Gallaher, P.K. Newby   +6 more
openalex   +1 more source

Exploratory Data Analysis to Identify the Relationship between Depression-Anxiety and Spiritual-Religious Factors among Undergraduate Students

, 2023
Nora Leticia Cuevas-Cuevas, Esperanza Carolina Orozco-del-Castillo   +1 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source