Results 71 to 80 of about 304,850 (274)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Educational Environments with Cultural and Religious Diversity: Psychometric Analysis of the Cyberbullying Scale

open access: yesReligions, 2019
The objective of this research is to adapt and validate a useful instrument to diagnose cyberbullying, provoked by intolerance towards cultural and religious diversity, identifying the profile of the aggressor and the victim.
María Tomé-Fernández   +2 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Analysis of Cybersecurity Awareness Among Social Media Users Among Teenagers Using Exploratory Factor Analysis (EFA) & Confirmatory Factor Analysis (CFA) Methods

open access: yesJournal of Electrical Engineering and Computer
Nowadays, security awareness is very important for social media users, especially teenagers. Many users become victims of cybercrime due to the lack of education about cybersecurity awareness.
Sofia Angela   +2 more
doaj   +1 more source

Development of a quantitative model for performance assessment of urban green buildings: exploratory and confirmatory factor analysis

open access: yesسلامت و محیط, 2022
Background and Objective: This study aims to develop a quantitative model for the performance evaluation of urban green buildings using exploratory and confirmatory factor analysis.
Hedieh Chorom   +2 more
doaj  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Factors that May Lead on the Non-renewal of Certified Organic Product According to Organic Producers in Brazil

open access: yesRevista de Economia e Sociologia Rural
: The regulatory process of the organic sector in Brazil began in 1999 and has gone through several changes, culminating in the Decree-Law of December 2007, which established rules for the production and trading of organic products in Brazil.
Andréa Rossi Scalco   +3 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Home - About - Disclaimer - Privacy