Results 41 to 50 of about 244,145 (258)
Closures of exponential families
, 2005 The variation distance closure of an exponential family with a convex set of canonical parameters is described, assuming no regularity conditions. The tools are the concepts of convex core of a measure and extension of an exponential family, introduced ...
Csiszar, Imre, Matus, Frantisek
core +1 more source
Targeted Maximum Likelihood Estimation using Exponential Families [PDF]
, 2014 Targeted maximum likelihood estimation (TMLE) is a general method for estimating parameters in semiparametric and nonparametric models. Each iteration of TMLE involves fitting a parametric submodel that targets the parameter of interest.
Díaz, Iván, Rosenblum, Michael
core +3 more sources
Rank verification for exponential families [PDF]
The Annals of Statistics, 2019 Many statistical experiments involve comparing multiple population groups. For example, a public opinion poll may ask which of several political candidates commands the most support; a social scientific survey may report the most common of several responses to a question; or, a clinical trial may compare binary patient outcomes under several treatment ...
Hung, Kenneth, Fithian, William
openaire +3 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Monitoring of Social Network and Change Detection by Applying Statistical Process: ERGM [PDF]
Journal of Optimization in Industrial Engineering, 2020 The statistical modeling of social network data needs much effort because of the complex dependence structure of the tie variables. In order to formulate such dependences, the statistical exponential families of distributions can provide a flexible ...
Farshid Rajabi +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Asymptotic optimality of sequential designs for estimation
International Journal of Mathematics and Mathematical Sciences, 1995 This paper is concerned with the problem of allocating a fixed number of trials between K independent populations from the exponential family, in order to estimate a linear combination of the means with squared error loss.
Kamel Rekab
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Journal of Biostatistics and Epidemiology, 2023 Many experts in the field of distribution theory have focused on extending probability distributions utilizing extended families of continuous distributions to improve the modeling adaptability of the conventional probability distributions.
Ibrahim Sule +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source