Results 101 to 110 of about 592,772 (239)

Markov processes and exponential families

open access: yesStochastic Processes and their Applications, 1992
AbstractWe study Markov processes the distribution of which stays for some interval of time in a given exponential family of distributions with one parameter. We show that the generator of such a process can be canonically associated to the generator of a Markov process on R, having the same stability property with respect to a natural exponential ...
openaire   +2 more sources

Engineering Light‐Element Modified LaFe11.6Si1.4 Compounds Enables Tunable Giant Magnetocaloric Effect

open access: yesAdvanced Science, EarlyView.
Herein, a tunable magnetocaloric effect is achieved on a series of light elements (C, F, S) modified LaFe11.6Si1.4 compounds. It is found that interstitial doping is more efficient in shifting TC compared with mixed (substitutional/interstitial) doping, but the first‐order transition cannot be well kept because of different p–d hybridization.
Fengqi Zhang   +13 more
wiley   +1 more source

Aqueous Two‐Phase Submicron Droplets Catalyze DNA Nanostructure Assembly for Confined Fluorescent Biosensing

open access: yesAdvanced Science, EarlyView.
Submicron droplets, formed by a polyethyleneglycol (PEG)/dextran aqueous two‐phase system·(ATPS), can act as catalytic centers that concentrate DNA and accelerate assembly kinetic in crowded environments. It highlights a cooperative mechanism wherein global crowding from PEG induces an excluded volume effect, while local crowding from dextran provides ...
Xiaoman Duan   +5 more
wiley   +1 more source

Generic A-family of exponential sums

open access: yesJournal of Number Theory, 2014
In this paper we construct a generating polynomial over the rationals for the generic Newton polygon for the L function of exponential sums of the family of f = x^d+ a x^s parameterized by a, and prove some of its key properties. The generating polynomial encodes information of and determines the generic Newton polygon at each prime p when p is large ...
openaire   +3 more sources

SCORT–Cas13d Nanotherapy Precisely Targets the ‘Undruggable’ Transcription Factor HoxB13 in Metastatic Prostate Cancer In Vivo

open access: yesAdvanced Science, EarlyView.
SCORT–Cas13d–pre‐gHoxB13 lipid nanoparticles precisely deliver Cas13d mRNA and guide RNAs to metastatic prostate tumors in the liver, knocking down the “undruggable” transcription factor HoxB13. This approach suppresses metastatic tumor growth, extends mouse survival, and does not induce major organ toxicity or immune activation, offering a safe and ...
Zhifen Cui   +15 more
wiley   +1 more source

A Self‐Assembling LYTAC Mediates CTGF Degradation and Remodels Inflammatory Tumor Microenvironment for Triple‐Negative Breast Cancer Therapy

open access: yesAdvanced Science, EarlyView.
A CTGF‐LYTAC nanoplatform is developed to selectively degrade connective tissue growth factor (CTGF) in triple‐negative breast cancer (TNBC), inhibiting TGF‐β signaling and cell interactions in the tumor microenvironment (TME). This strategy effectively suppresses tumor growth and metastasis, outperforming antibody‐based therapy.
Jia‐Yi Lin   +11 more
wiley   +1 more source

Correlations in Magnetic Sub‐Domains as an Unconventional Phase Diagram for van der Waals Ferromagnets

open access: yesAdvanced Science, EarlyView.
An unconventional magnetic order is observed in exfoliated CrBr3 layers, characterized by vertically correlated planar magnetic sub‐domains. Magnetic force microscopy, ab initio calculations, and micromagnetic simulations indicate that these sub‐domains arise from stacking faults modifying interlayer exchange coupling.
Sergey Y. Grebenchuk   +9 more
wiley   +1 more source

Explainable Deep Multilevel Attention Learning for Predicting Protein Carbonylation Sites

open access: yesAdvanced Science, EarlyView.
Selective carbonylation sites (SCANS) are conceptualized, designed, evaluated, and released. SCANS captures segment‐level, protein‐level, and residue embeddings features. It utilizes elaborate loss function to penalize cross‐predictions at the residue level.
Jian Zhang   +6 more
wiley   +1 more source

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