Results 41 to 50 of about 387,303 (294)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Towards Large-scale Functional Verification of Universal Quantum Circuits [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2019
We introduce a framework for the formal specification and verification of quantum circuits based on the Feynman path integral. Our formalism, built around exponential sums of polynomial functions, provides a structured and natural way of specifying ...
Matthew Amy
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Moments, Exponential Sums, and Monodromy Groups

open access: yesForum of Mathematics, Sigma
We determine the geometric monodromy groups attached to various families, both one-parameter and multi-parameter, of exponential sums over finite fields, or, more precisely, the geometric monodromy groups of the $\ell $ -adic local systems on ...
Nicholas M. Katz, Pham Huu Tiep
doaj   +1 more source

Stability Analysis of Discrete-Time Stochastic Delay Systems with Impulses

open access: yesMathematics, 2021
This paper is concerned with stability analysis of discrete-time stochastic delay systems with impulses. By using the sums average value of the time-varying coefficients and the average impulsive interval, two sufficient criteria for exponential ...
Ting Cai, Pei Cheng
doaj   +1 more source

Bounds for a spectral exponential sum [PDF]

open access: yesJournal of the London Mathematical Society, 2018
We prove new upper bounds for a spectral exponential sum by refining the process by which one evaluates mean values of $L$-functions multiplied by an oscillating function. In particular, we introduce a method which is capable of taking into consideration the oscillatory behaviour of the function.
Olga Balkanova, Dmitry Frolenkov
openaire   +3 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

On the fourth power mean of the generalized three-term exponential sums

open access: yes四川大学学报. 自然科学版, 2020
This paper aims at calculation of the fourth power mean of a certain generalized three-term exponential sums modulo p, an odd prime.By using some properties of the classical Gauss sums and character sums, we give some exact calculating formulae and ...
Tang Rui, CHEN Long
doaj  

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