Results 61 to 70 of about 168,623 (324)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

On the Hybrid Fourth Power Mean Involving Legendre’s Symbol and One Kind Two-Term Exponential Sums

open access: yesJournal of Mathematics, 2021
The main purpose of this article is using the elementary methods and the properties of the quadratic residue modulo an odd prime p to study the calculating problem of the fourth power mean of one kind two-term exponential sums and give an interesting ...
Jingzhe Wang
doaj   +1 more source

Exponential Sums and Congruences with Factorials

open access: yes, 2004
We estimate the number of solutions of certain diagonal congruences involving factorials. We use these results to bound exponential sums with products of two factorials $n!m!$ and also derive asymptotic formulas for the number of solutions of various ...
Garaev, Moubariz Z.   +2 more
core   +1 more source

Bounds for a spectral exponential sum [PDF]

open access: yesJournal of the London Mathematical Society, 2018
We prove new upper bounds for a spectral exponential sum by refining the process by which one evaluates mean values of $L$-functions multiplied by an oscillating function. In particular, we introduce a method which is capable of taking into consideration the oscillatory behaviour of the function.
Olga Balkanova, Dmitry Frolenkov
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

On the recursive properties of one kind hybrid power mean involving two-term exponential sums and Gauss sums

open access: yesOpen Mathematics, 2018
The main purpose of this paper is to study the computational problem of one kind hybrid power mean involving two-term exponential sums and quartic Gauss sums using the analytic method and the properties of the classical Gauss sums, and to prove some ...
Shen Shimeng
doaj   +1 more source

The distribution of the maximum of character sums

open access: yes, 2012
We obtain explicit bounds on the moments of character sums, refining estimates of Montgomery and Vaughan. As an application we obtain results on the distribution of the maximal magnitude of character sums normalized by the square root of the modulus ...
Granville   +2 more
core   +1 more source

A Note on Exponential Sums

open access: yesFinite Fields and Their Applications, 1995
This paper along with \textit{J. Angel} [Finite Fields Appl. 2, 62-86 (1996; see the preceding review)] and \textit{R. Evans} [Finite Fields Appl. 1, 376-394 (1995; Zbl 0844.11078)] proves that finite upper half plane graphs are Ramanujan in characteristic 2. Ramanujan graphs were first defined by \textit{A. Lubotzky}, \textit{R.
openaire   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

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