Results 81 to 90 of about 168,623 (324)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

A Novel Integral Equation for the Riemann Zeta Function and Large t-Asymptotics

Mathematics, 2019
Based on the new approach to Lindelöf hypothesis recently introduced by one of the authors, we first derive a novel integral equation for the square of the absolute value of the Riemann zeta function.
Konstantinos Kalimeris, Athanassios S. Fokas   +1 more
doaj   +1 more source

A Generalized Equilibrium Transform with Application to Error Bounds in the Rényi Theorem with No Support Constraints

Mathematics, 2020
We introduce a generalized stationary renewal distribution (also called the equilibrium transform) for arbitrary distributions with finite nonzero first moment and study its properties.
Irina Shevtsova, Mikhail Tselishchev
doaj   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

INCOMPLETE EXPONENTIAL SUMS OVER EXPONENTIAL FUNCTIONS [PDF]

The Quarterly Journal of Mathematics, 2014
We extend some methods of bounding exponential sums of the type $\displaystyle\sum_{n\le N}e^{2πiag^n/p}$ to deal with the case when $g$ is not necessarily a primitive root. We also show some recent results of Shkredov concerning additive properties of multiplicative subgroups imply new bounds for the sums under consideration.
openaire   +2 more sources

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Generating Functions for New Families of Combinatorial Numbers and Polynomials: Approach to Poisson–Charlier Polynomials and Probability Distribution Function

Axioms, 2019
The aim of this paper is to construct generating functions for new families of combinatorial numbers and polynomials. By using these generating functions with their functional and differential equations, we not only investigate properties of these new ...
Irem Kucukoglu, Burcin Simsek, Yilmaz Simsek   +2 more
doaj   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

An exact renormalization formula for Gaussian exponential sums and applications

, 2009
In the present paper, we derive a renormalization formula "\`a la Hardy-Littlewood" for the Gaussian exponential sums with an exact formula for the remainder term.
Fedotov, Alexander, Klopp, Frédéric
core   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source