Results 31 to 40 of about 9,640 (238)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
On Pseudopoints of Algebraic Curves
, 2010 Following Kraitchik and Lehmer, we say that a positive integer $n\equiv1\pmod 8$ is an $x$-pseudosquare if it is a quadratic residue for each odd prime $p\le x$, yet is not a square. We extend this defintion to algebraic curves and say that $n$ is an $x$-
Farashahi, Reza R., Shparlinski, Igor E.
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Pair Correlation of Zeros, Primes in Short Intervals and Exponential Sums over Primes
Journal of Number Theory, 2000 Let \(S(\alpha) = \sum_{n\leq X}\Lambda(n)e(n\alpha)\), where \(e(x)=e^{2\pi ix}\), and \(\Lambda(n)\) is the von Mangoldt function defined to be \(\log p\) if \(n=p^m\), \(p\) a prime, \(m\geq 1\), and zero otherwise. This paper is concerned with the short \(L^2\) mean \[ S(X,\xi) = \int_{-\xi}^\xi |S(\alpha)|^2 d\alpha , \] with \(0\leq \xi \leq {1 ...
A. LANGUASCO, PERELLI, ALBERTO
openaire +3 more sources
FEBS Open Bio, EarlyView.KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
A Bombieri–Vinogradov-type result for exponential sums over Piatetski-Shapiro primes
Lithuanian Mathematical Journal, 2022 In this paper, we establish a theorem of Bombieri -- Vinogradov type for exponential sums over Piatetski-Shapiro primes $p= [n^{1/γ}]$ with $\frac{865}{886}
openaire +2 more sources
On matrix elements for the quantized cat map modulo prime powers
, 2008 The quantum cat map is a model for a quantum system with underlying chaotic dynamics. In this paper we study the matrix elements of smooth observables in this model, when taking arithmetic symmetries into account. We give explicit formulas for the matrix
Kelmer, Dubi
core +3 more sources
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Vinogradov's three primes theorem with almost twin primes
, 2017 In this paper we prove two results concerning Vinogradov's three primes theorem with primes that can be called almost twin primes. First, for any $m$, every sufficiently large odd integer $N$ can be written as a sum of three primes $p_1, p_2$ and $p_3 ...
Matomäki, Kaisa, Shao, Xuancheng
core +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source