Results 91 to 100 of about 92,378 (309)

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Suppression of Antifolate Resistance by Targeting the Myosin Va Trafficking Pathway in Melanoma

Neoplasia: An International Journal for Oncology Research, 2013
Human melanoma is a significant clinical problem. As most melanoma patients relapse with lethal drug-resistant disease, understanding and preventing mechanism(s) of resistance is one of the highest priorities to improve melanoma therapy.
María Piedad Fernández-Pérez, María F. Montenegro, Magalí Sáez-Ayala, Luis Sánchez-del-Campo, Antonio Piñero-Madrona, Juan Cabezas-Herrera, José Neptuno Rodríguez-López   +6 more
doaj   +1 more source

Energy security for Bangladesh : prospects and strategic implications of natural gas [PDF]

, 2004
Includes bibliographical references (p. 25-26). "May 2004."An overview of the energy scenario in Bangladesh, with a focus on natural gas. Includes discussion of the exploration, production, and consumption of natural gas, along with strategic options for
Samrina, Nawrin
core  

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Formal and informal social care in people with Rheumatic and Musculoskeletal diseases: a cross‐sectional multicentre survey

Arthritis Care &Research, Accepted Article.
Introduction Rheumatic and musculoskeletal diseases(RMDs) are leading causes of physical disability, necessitating support with activities of daily living(ADLs). This study describes social care received by patients with RMDs in two disperate regions of England: Salford(urban) and Norfolk(rural).
Mehreen Somro, Karen Durrant, William G Dixon, John McBeth, Alex MacGregor, Max Yates, Jenny H Humphreys   +6 more
wiley   +1 more source

Taking tissue seriously means taking communities seriously

BMC Medical Ethics, 2007
Background Health research is increasingly being conducted on a global scale, particularly in the developing world to address leading causes of morbidity and mortality. While research interest has increased, building scientific capacity in the developing
Lavery James V, Upshur Ross EG, Tindana Paulina O   +2 more
doaj   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Fluxo de mercadorias internacionais no periodo da pandemia da covid-19 no município de Santana – Amapá

Confins
Amidst the uncertainty and volatility in the movement of international goods flow until 2022, a new factor emerged in February 2020, compressing international trade: Covid-19 and its impact on the global economy.
Adan Guilherme da Silva Morales, Johnatas Cavalcante Melo, Sérgio Barbosa de Miranda, José Manoel Balthazar, Lidiane de Vilhena Amanajás Miranda   +4 more
doaj   +1 more source

EBSD Study of Creep‐Induced Lattice Misorientation in MgO‐Particle‐Reinforced Austenitic Steel Composites

Advanced Engineering Materials, EarlyView.
Creep experiments at 900°C on coarse‐grained steel‐ceramic composites containing recycled magnesia reveal that higher ceramic volume fractions significantly enhance the creep resistance. Detailed EBSD investigations identify subgrain formation in the steel matrix as the dominant deformation mechanism.
Moritz Müller, Amaya Compart, Mahnaz Mehdizadehlima, Serhii Yaroshevskyi, Christos G. Aneziris, Horst Biermann, Anja Weidner   +6 more
wiley   +1 more source

Sonora State Producer and Strategic Exporter of Copper

Expert Journal of Economics, 2017
This paper presents a study on the importance of copper production in the State of Sonora, Mexico. Important data will be presented with total relevance to the current economic framework in which it will be possible to determine through a thorough ...
Rosalina JAIME MEULY, Daniela GORMITH
doaj