Results 81 to 90 of about 92,378 (309)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Metodología DID-Matching aplicada a la política pública de promoción de exportaciones

open access: yesEstudios de Administración, 2009
This article shows how the Did Matching Methodology as an impact evaluation tool can be applied to a specific exportation public policyinstrument, called Export Marketing Assistance (EMA).
Valeska V. Geldres W.   +2 more
doaj   +1 more source

China-U.S. Potential Non-food Ethanol Exportation [PDF]

open access: yes
To reduce national oil dependency, ethanol has been given a center stage of U.S. energy sources. The Renewable Fuel Standard (RFS) program was launched to increase the volume of renewable gasoline from 9 billion gallons in 2008 to 36 billion gallons by ...
Li, Tongzhe   +2 more
core   +1 more source

Camel economy: from local to international market [PDF]

open access: yes, 2015
The camel productions are involved in local, regional or international economy. If the market of live animals, linked mainly to the meat market, is well developed in the Horn of Africa and Middle-east, the milk market knows a recent development in spite ...
Bengoumi, Mohammed, Faye, Bernard
core  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Does China's Trade Expansion Help African Development? - A South-South Trade Model Approach [PDF]

open access: yes
With the aim to explain the explosive growth of trade between China and Africa, especially the impacts of China's exportation on African countries, a simple South-South trade model is constructed to formulate the idea that for a technologically backward ...
Yong He
core  

A Letter from the Council of the Colony of Massachusetts Bay to the Council of Connecticut [PDF]

open access: yes, 1921
Written April 7, 1676, by Edward Rawson, the Secretary. Issued at the General Court of the Society of Colonial Wars in the State of Rhode Island and Providence Plantations by its Governor, Frederick Dickman Carr, Esq.
Rawson, Edward
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Taxation if Capital is not Perfectly Mobile: Tax Competition versus Tax Exportation. [PDF]

open access: yes
This paper analyzes the tax competition and tax exporting effect of financial integration. On the one hand, financial integration increases capital mobility and thus the incentive for countries to compete for capital.
Sylvester C.W. Eijffinger, Wolf Wagner
core  

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