Results 81 to 90 of about 17,830 (305)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Metodología DID-Matching aplicada a la política pública de promoción de exportaciones

open access: yesEstudios de Administración, 2009
This article shows how the Did Matching Methodology as an impact evaluation tool can be applied to a specific exportation public policyinstrument, called Export Marketing Assistance (EMA).
Valeska V. Geldres W.   +2 more
doaj   +1 more source

Exportation d'énergie de Roumanie en Tchécoslovaquie. —

open access: yes, 1960
Georges Pierre. Exportation d'énergie de Roumanie en Tchécoslovaquie. — . In: Annales de Géographie, t. 69, n°372, 1960.
George, Pierre
core  

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

Innovation and exportation of portuguese companies

open access: yes, 2018
Dissertação de mestrado em Economia Industrial e da EmpresaA presente dissertação tem como objetivo principal analisar a relação inovação – exportação das empresas portuguesas, ou seja, perceber de que forma a atividade inovadora impulsiona a atividade
Ribeiro, Vânia Letícia Valbom
core  

Formal and Informal Social Care in People With Rheumatic and Musculoskeletal Diseases: A Cross‐Sectional Multicenter Survey

open access: yesArthritis Care &Research, EarlyView.
Objective Rheumatic and musculoskeletal diseases (RMDs) are leading causes of physical disability, necessitating support with activities of daily living. This study describes social care received by patients with RMDs in two disparate regions of England: Salford (urban) and Norfolk (rural).
Mehreen Somro   +6 more
wiley   +1 more source

An Economic Analysis of the Special Milk Classes Scheme of Canada and the Agricultural Subsidy [PDF]

open access: yes
We examine the effects of Canada's Special Milk Classes Scheme on resource allocation and discuss the rationale for average total cost of production as a measure of payments.
ABE Kenzo
core  

Enterprises' internationalisation strategy: skills in exportation and customs law [PDF]

open access: yes, 2013
Economical development has always been connected to the commercial exchanges between people, due to the necessity to suppress their needs. With the increasing growth of international business and more competitive and demanding markets, exportation has ...
dias pinto ribeiro, maria clara   +1 more
core  

Nutrient extraction and exportation by castor bean hybrid lyra [PDF]

open access: yes, 2012
Information about nutrient extraction and exportation by crops, as well as the periods of highest nutrient demand is important for an adequate fertilization management.
Martha Santana do Nascimento   +15 more
core   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

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