Results 221 to 230 of about 92,378 (309)

Graphs and notes on the economic situation in the Community = Graphiques et notes rapides sur la conjoncture dans la Communaute No. 2, 1969 [PDF]

, 1969

core  

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Arginine Delays Postharvest Softening of Button Mushroom (<i>Agaricus bisporus</i>) via Lipid Metabolism Regulation. [PDF]

Foods
Xu D, Gao L, Mu X, Wang T, Liang J, Wang Q, Niu Q.   +6 more
europepmc   +1 more source

Nam Theun 2 Hydroelectric Project. Nakai livelihood implementation plant focus on agriculture livestock. Option : agriculture, livestock, forestry, fisheries integration [PDF]

, 2006
Chabanne, André, Julien, Patrick
core  

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

Advanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

Self-consistent gravity model for inferring node mass in flow networks. [PDF]

Sci Rep
Lee D, Cho W, Kim H, Kim G, Jeong HC, Kim BJ.   +5 more
europepmc   +1 more source

Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids

Advanced Science, EarlyView.
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang, David W. McKellar, Andrew Kowalczewski, Nhu Y. Mai, Meng Chai, Xiaojun L. Lian, Yi Zheng, Jeffrey Amack, Nathan Tucker, Iwijn De Vlaminck, Huaxiao Yang, Benjamin D. Cosgrove, Zhen Ma   +12 more
wiley   +1 more source

Exports, Export Destinations, and Skills

, 2010
Irene Brambilla, Daniel Lederman, Guido Porto   +2 more
openaire   +2 more sources

Vector surveillance during a major chikungunya outbreak in northwestern São Paulo state, Brazil. [PDF]

Npj Viruses
Banho CA, Parra MCP, Nascimento OB, Magnani GP, Ferreira MVM, Lemos AP, Lourenço KL, de Carvalho Marques B, Brancini ML, Sacchetto L, Negri AF, Menezes RMT, de Deus JT, Estofolete CF, Júnior JPA, Vasilakis N, Nogueira ML.   +16 more
europepmc   +1 more source

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

Advanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min, Nam Than, Yong Cheol Shin, Elif G. Ertugral, Chandrasekhar R. Kothapalli, Olumuyiwa Awoniyi, Hyun Jung Kim   +6 more
wiley   +1 more source