Results 51 to 60 of about 17,830 (305)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Revista de Economia e Sociologia RuralResumo: O comércio internacional de pescados vem se destacando nas últimas décadas, pois é apontado como de ampla competição. Como forma de entender a dinâmica desse comércio, o objetivo da pesquisa foi caracterizar o desempenho histórico dos países ...
Alessandra Cristina da Silva Farias +1 more
doaj +1 more source
Revista de Economia e Sociologia Rural, 2007 A fruticultura é uma atividade de grande importância na balança comercial brasileira e mais ainda para a região Nordeste. As diversas exigências do mercado exportador de frutas, como os certificados de qualidade, aliadas aos entraves internos da produção
Luciano Menezes Bezerra Sampaio
doaj +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Dinâmica de Exportação: A Internalização do Preço da Soja em Grão Brasileira
Revista de Economia Mackenzie, 2005 The soy is one commodity agriculturist of great exposition in the external market what it generates the sensitivity of the formation of its domestic price to the evolution of the prices practiced in the international trade, specifically to the ones of
Caroline Miriã Fontes Martins +1 more
doaj
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
AN ECONOMIC STUDY FOR SOME DETERMINANTS COMPETITlVE CENTER OF THE EGYPTION ORANGES EXPORTS [PDF]
Journal of Agricultural Economics and Social Sciences, 2006 Oranges is considered one of the most inportant of export crop . Although it has acomparative advantage in the domestic. production, the exportation quntity reducted in the last years. This study carried out to the factors affecting on the exportation
Y. Ahmed
doaj +1 more source