Results 11 to 20 of about 40,637 (278)

Coupling of Termination, 3′ Processing, and mRNA Export [PDF]

Molecular and Cellular Biology, 2002
In a screen to identify genes required for mRNA export in Saccharomyces cerevisiae, we isolated an allele of poly(A) polymerase (PAP1) and novel alleles encoding several other 3' processing factors. Many newly isolated and some previously described mutants (rna14-48, rna14-49, rna14-64, rna15-58, and pcf11-1 strains) are defective in polymerase II (Pol
Hammell, C M, Gross, Stefan, Zenklusen, Daniel, Heath, Catherine V, Stutz, Françoise, Moore, Claire, Cole, C N   +6 more
openaire   +5 more sources

Factors influencing livestock export in Somaliland’s terminal markets [PDF]

Pastoralism, 2020
AbstractLivestock export from Somaliland to the Arabian Peninsula countries is an important economic activity and the main source of Somaliland’s foreign exchange earnings. We have employed multiple regression time series analysis of secondary data to understand factors that influence the monthly volumes of small ruminants (sheep and goats) and cattle ...
Ahmed Musa, Oliver Vivian Wasonga, Nadhem Mtimet   +2 more
openaire   +3 more sources

C-Terminal Ubiquitination of p53 Contributes to Nuclear Export [PDF]

Molecular and Cellular Biology, 2001
The growth inhibitory functions of p53 are controlled in unstressed cells by rapid degradation of the p53 protein. One of the principal regulators of p53 stability is MDM2, a RING finger protein that functions as an E3 ligase to ubiquitinate p53. MDM2 promotes p53 nuclear export, and in this study, we show that ubiquitination of the C terminus of p53 ...
M A, Lohrum, D B, Woods, R L, Ludwig, E, Bálint, K H, Vousden   +4 more
openaire   +2 more sources

N-terminal processing of proteins exported by malaria parasites [PDF]

Molecular and Biochemical Parasitology, 2008
Malaria parasites utilize a short N-terminal amino acid motif termed the Plasmodium export element (PEXEL) to export an array of proteins to the host erythrocyte during blood stage infection. Using immunoaffinity chromatography and mass spectrometry, insight into this signal-mediated trafficking mechanism was gained by discovering that the PEXEL motif ...
Henry H, Chang, Arnold M, Falick, Peter M, Carlton, John W, Sedat, Joseph L, DeRisi, Michael A, Marletta   +5 more
openaire   +2 more sources

Twin arginine translocation system in secretory expression of recombinant human growth hormone

Research in Pharmaceutical Sciences, 2016
Recombinant protein production in E. coli has several advantages over other expression systems. Misfolding, inclusion body formation, and lack of eukaryotic post translational modification are the most disadvantages of this system. Exporting of correctly
Mohammad Reza Bagherinejad, Hamid Mir-Mohammad Sadeghi, Daryoush Abedi, C Perry Chou, Fatemeh Moazen, Mohammad Rabbani   +5 more
doaj   +1 more source

What constrains Africa's exports? [PDF]

, 2010
This paper examines the effects of transit, documentation, and ports and customs delays on Africa’s exports. The authors find that transit delays have the most economically and statically significant effect on exports.
Freund , Caroline L., Rocha, Nadia
core   +2 more sources

Dimerization of ABCG2 analysed by bimolecular fluorescence complementation.

PLoS ONE, 2011
ABCG2 is one of three human ATP binding cassette transporters that are functionally capable of exporting a diverse range of substrates from cells. The physiological consequence of ABCG2 multidrug transport activity in leukaemia, and some solid tumours is
Ameena J Haider, Deborah Briggs, Tim J Self, Hannah L Chilvers, Nicholas D Holliday, Ian D Kerr   +5 more
doaj   +1 more source

Engineering the Salmonella type III secretion system to export spider silk monomers

Molecular Systems Biology, 2009
The type III secretion system (T3SS) exports proteins from the cytoplasm, through both the inner and outer membranes, to the external environment. Here, a system is constructed to harness the T3SS encoded within Salmonella Pathogeneity Island 1 to export
Daniel M Widmaier, Danielle Tullman‐Ercek, Ethan A Mirsky, Rena Hill, Sridhar Govindarajan, Jeremy Minshull, Christopher A Voigt   +6 more
doaj   +1 more source

Effect of Twine-arginine Translocation-signaling Fusion System and Chaperones Co-expression on Secretory Expression of Somatropin

Advanced Biomedical Research, 2018
Background: Twine-arginine translocation (TAT) system is one of the exporting systems in Escherichia coli which could transport fully/semi-correctly folded proteins outside the reductive cytoplasmic space.
Mohammad Reza Bagherinejad, Hamid Mir-Mohammad Sadeghi, Daryoush Abedi, Fateme Moazen, Mohammad Rabbani   +4 more
doaj   +1 more source

Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis

Haematologica, 2019
Loss-of-function mutations in the ATP-binding cassette (ABC) transporter of the inner mitochondrial membrane, ABCB7, cause X-linked sideroblastic anemia with ataxia, a phenotype that remains largely unexplained by the proposed role of ABCB7 in exporting ...
Nunziata Maio, Ki Soon Kim, Gregory Holmes-Hampton, Anamika Singh, Tracey A. Rouault   +4 more
doaj   +1 more source