Results 41 to 50 of about 40,637 (278)

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

open access: yesAdvanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour   +11 more
wiley   +1 more source

Tax compliance cost and international trade in Africa [PDF]

open access: yes, 2019
International trade in Africa could be one of the antidotes to the precarious poverty and economic deficiency in which the continent finds itself. An outward orientation towards international trade opens the continent to many opportunities including an ...
Ablorde, Francis   +3 more
core  

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

open access: yesAdvanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement   +12 more
wiley   +1 more source

Erratum: Canonical Wnt signalling regulates nuclear export of Setdb1 during skeletal muscle terminal differentiation [PDF]

open access: yesCell Discovery, 2016
Correction to: Cell Discovery (2016) 2, 16037; doi:10.1038/celldisc.2016.37; Published 18 October 2016 In the initial published version of this article, an error was made in Figure 6c, where the titles of x axis and y axis were left out. The corrected Figure 6c is now attached in this corrigendum. All figures and text description other than this remain
Beyer, Sophie   +6 more
openaire   +3 more sources

Mesenchymal Stem Cell‐Derived Apoptotic Micro‐Vesicles Repaired Sciatic Nerve Defect by Regulating Early Inflammatory Microenvironment and Promoting Angiogenesis

open access: yesAdvanced Healthcare Materials, EarlyView.
HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu   +21 more
wiley   +1 more source

Perfusion Bioreactor Culture Incorporating Mechanical Confinement Enhances Mesenchymal Stem Cell Extracellular Vesicle Production and Wound Healing Potential

open access: yesAdvanced Materials Technologies, EarlyView.
Scalable manufacturing challenges and limited potency remain two of the most intransigent issues limiting clinical translation of EV therapeutics. Mechanical cues can induce phenotypic changes and increased vesiculation in EV source cells without the use of extraneous reagents, chemicals, and/or cargo, thereby potentially drastically improving the ...
Emily H. Powsner   +10 more
wiley   +1 more source

Design Optimization of a Variable Stiffness Robotic Gripper with Passive Restoration Fabricated by Multimaterial 3D Printing

open access: yesAdvanced Robotics Research, EarlyView.
A multimaterial robotic gripper fabricated via multimaterial 3D printing integrates conductive thermopolymer joints with flexible elastomeric components. Joule heating enables precise joint‐level stiffness modulation, enhanced by embedded temperature sensors, passive shape restoration, and active cooling, enabling versatile manipulation capabilities ...
Daniel Jee Seng Goh   +4 more
wiley   +1 more source

Growing exports and new prospects for russian lentils

open access: yesМодели, системы, сети в экономике, технике, природе и обществе
Background. The relevance of the study is confirmed by the growing interest in lentils around the world and corresponds to the targets and tasks established by Decree of the President of the Russian Federation of 07.05.2024 № 309 "On the national ...
N.Yu. Polunina
doaj   +1 more source

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